Publications by authors named "Lanjiao Li"
High-performance near-infrared (NIR) light sources are highly sought after in advanced spectroscopy techniques, driving the development of NIR phosphor-converted light-emitting diodes (pc-LEDs). Escalating the luminescence intensity and thermal stability of NIR-emitting phosphors, which is a core component of NIR pc-LEDs, is of paramount importance. Herein, chemical unit cosubstitution and cosolvent addition tactics were implemented to simultaneously boost the NIR luminescence performance of the synthesized phosphors.
View Article and Find Full Text PDFIntroduction: This study examined the impact of 5'-(N- ethylcarboxamido)adenosine (NECA) in the peripheral blood of healthy individuals, those with diabetes mellitus, diabetic retinopathy (DR), and C57BL/6 mice, both and .
Methods: Enzyme-linked immunosorbent assay (ELISA) and flow cytometry (FCM) were used to evaluate the effects of NECA on dendritic cells (DCs) and mouse bone marrow-derived dendritic cells (BMDCs) and the effects of NECA-treated DCs on Treg and Th17 cells. The effect of NECA on the Toll-like receptor (TLR) pathway in DCs was evaluated using polymerase chain reaction (PCR) and western blotting (WB).
Article Synopsis
- 5α-Hydroxycostic acid, derived from the plant Laggera alata, shows potential as a treatment for choroidal neovascularization (CNV) by inhibiting the formation and leakage of these abnormal blood vessels.* -
- The study utilized both in vitro and in vivo models to analyze the effects of 5α-Hydroxycostic acid on cell proliferation, migration, and tubule formation, highlighting its ability to improve cell adhesion by targeting specific signaling pathways.* -
- Results indicate that this compound effectively reduces vascular leakage and suggests that its mechanisms of action involve interference with the VEGF/VEGFR and Ang2/Tie2 pathways, making it a promising candidate for CNV therapy
Article Synopsis
- * Researchers have developed Angiopoietin1-anti CD105-PLGA nanoparticles (AAP NPs), which noninvasively target CNV, enhance drug delivery, and improve vascular stability while reducing leakage.
- * In animal studies, AAP NPs showed significant therapeutic effects in decreasing CNV leakage, offering a promising alternative for treating AMD without the complications of current methods.
Objective: The aim of this study was to investigate whether the gene polymorphisms of vitamin D receptor (VDR) had a genetic effect on the susceptibility of Behcet's disease (BD).
Material And Methods: We conducted a meta-analysis emphasizing the association between the VDR gene polymorphisms and the risk of BD. The strength of the association in five genetic models was assessed by pooled odds ratios (OR) with a corresponding 95%confidence interval (CI).