Variation of Bruch's membrane opening in response to intraocular pressure change during scleral lens wear, in a population with keratoconus.

Purpose: The present study aimed to determine the potential impact of scleral lenses on intraocular pressure (IOP) by analysing the Bruch's membrane opening-minimum rim width (BMO-MRW) while the lenses are worn, in a population with keratoconus.

Methods: Participants were required to have keratoconus and be successfully fitted with scleral lenses for at least 3 months. A new pair of optimised scleral lenses was provided before the study.

Effects of Optical Zone Variation of High-Addition Multifocal Contact Lenses on the Global Flash Multifocal Electroretinography.

Objectives: To evaluate the retinal response to myopic defocus after the wear of soft multifocal contact lenses with high addition through electroretinography.

Methods: Twenty-seven participants meeting inclusion criteria were enrolled. Tropicamide 1% drops (2) were instilled.

Translation and validation of the contact lens dry eye questionnaire 8 (CLDEQ-8) in Canadian French.

Purpose: To present the process that led to the creation of the French Canadian translated version of the Contact Lens Dry Eye Questionnaire-8 (which allows for an assessment of symptoms while wearing soft contact lenses) as well as the validation data of the f-CLDEQ-8.

Methods: The CLDEQ-8 went through the process of reverse translation, which was then reviewed and improved by an experts' committee to create a first version of the French questionnaire. Cognitive interviews were conducted to pretest the tool and ensure content validity.

Frequency Doubling Technology Visual Field Loss in Fabry Subjects Related to Retinal Ganglion Cell Function as Explored by ERG and OSOME.

Purpose: This study aims to evaluate potential causes of FDT visual field loss in a selected group of Fabry subjects.

Patients And Methods: This is a pilot observational study. Subjects were assessed during 2 visits.

CLEAR - Orthokeratology.

Orthokeratology (ortho-k) is the process of deliberately reshaping the anterior cornea by utilising specialty contact lenses to temporarily and reversibly reduce refractive error after lens removal. Modern ortho-k utilises reverse geometry lens designs, made with highly oxygen permeable rigid materials, worn overnight to reshape the anterior cornea and provide temporary correction of refractive error. More recently, ortho-k has been extensively used to slow the progression of myopia in children.

Bruch Membrane Opening Minimum Rim Width Changes During Scleral Lens Wear.

Objective: The purpose of this study was to evaluate the change in Bruch membrane opening minimum rim width (BMO-MRW) during scleral lens (SL) wear.

Methods: Twenty young white subjects were enrolled (10 women and 10 men); preliminary evaluation consisted of serial measurements of intraocular pressure (IOP) using a dynamic noncontact tonometer (Corvis, Oculus), which also yielded a corneal biomechanical index and central corneal thickness, and BMO-MRW using optical coherence tomography imaging (OCT) imaging (Spectralis, Heidelberg) through 6 hrs to establish normative diurnal curves. The next day, participants were fitted with a 16-mm SL on one eye, and OCT measurements were repeated over the same time span.

Corneal Endothelial Blebs Induced in Scleral Lens Wearers.

Significance: In the bleb phenomenon, some endothelial cells transiently lose their specular reflection. This has been reported during contact lens wear and goggle-induced hypoxia or hypercapnia.

Purpose: The purposes of this study were to determine whether blebs appear after scleral lens wear and if their appearance is influenced by lens clearance and to compare bleb and cell sizes.

The official guide to scleral lens terminology.

Purpose: In absence of scleral lens standards, this article aims to provide an official definition of terms related to scleral lens fitting and manufacturing, in order to make more uniform the use of appropriate terms when describing, writing or lecturing about scelral lenses. Adoption of a common terminology may also favor more fruitful exchanges between eyecare practitioners and manufacturers.

Methods: A committee of 12 advances scleral lens clinicians met and develop a list of terms related to scleral lens fit and manufacturing.

Longitudinal study on ocular manifestations in a cohort of patients with Fabry disease.

Purpose: This study aims to assess the evolution of ocular manifestations in a cohort of Fabry patients.

Methods: This is a prospective observational study conducted from 2013 to 2017 (5 consecutive exams). All subjects underwent a comprehensive ocular examination including oriented case history, refraction, corneal topography, biomechanical corneal properties and pachometry assessments, aberrometry, anterior segment evaluation, double-frequency visual field (FDT), intra-ocular pressure, and ocular fundus.

Intra-ocular pressure variation associated with the wear of scleral lenses of different diameters.

Purpose: To evaluate the variation of intra-ocular pressure during scleral lens wear, and the influence of the lens diameter on the results.

Methods: This is a prospective, randomized study performed on Caucasian subjects (16 F; 5 M), aged 24.7 + 4.

Effects of Scleral-lens Tear Clearance on Corneal Edema and Post-lens Tear Dynamics: A Pilot Study.

Significance: The present study with small-diameter scleral lenses (SLs) revealed that post-lens tear thickness (PoLTT) was significantly associated with post-lens tear mixing, but not with central corneal edema, after short-term SL wear.

Purpose: The aim of this study was to investigate the influence of SL tear clearance (PoLTT) on central corneal thickness and post-lens tear dynamics during 5-hour lens wear.

Methods: Neophytes with no active ocular disease were fitted bilaterally with SLs (hofocon A; 15.

Analysis of Two Orthokeratology Lens Designs and Comparison of Their Optical Effects on the Cornea.

Purpose: This study aims to analyze two commercial orthokeratology lens designs and compare their optical effects at the corneal level.

Methods: This is a retrospective study on subjects seeking an orthokeratology fitting for myopia management at the Université de Montréal clinic between January 2013 and August 2015. Group A included the first 64 subjects fitted with a 4-curve lens design (Paragon CRT; Paragon) who met the inclusion criteria, whereas group B included the same number of subjects fitted with a 5-curve lens design (Dreamlens; Polymer Technology, Rochester, NY).

Variation of clearance considering viscosity of the solution used in the reservoir and following scleral lens wear over time.

Purpose: This study aims to evaluate the settling of a scleral lens and if this process is influenced by the nature of the fluid layer.

Methods: A prospective, non-randomized control study was performed using an 18mm scleral lens. They were fitted with a central clearance of 400 um at insertion.

Oxygen Tension Beneath Scleral Lenses of Different Clearances.

Purpose: To evaluate the relative partial pressure in oxygen (pO2) at the corneal surface under Boston XO2 scleral lenses (SL) fitted with targeted clearances of 200 and 400 μm (SL200 and SL400).

Methods: During this prospective study, the right eyes of eight normal subjects were fitted with SL200 and SL400. Clearance, validated after 5 minutes of wear with an optical coherence tomograph, was used with lens thicknesses to calculate transmissibility and estimate pO2.

Clinical Evaluation of Large Diameter Rigid-Gas Permeable Versus Soft Toric Contact Lenses for the Correction of Refractive Astigmatism. A MultiCenter Study.

Purpose: This study aims to address the clinical performance of a large diameter rigid gas permeable lens (LRGP) in a group of subjects with low-to-moderate (0.75-2.75 D) refractive astigmatism.

Comparing two different daily disposable lenses for improving discomfort related to contact lens wear.

Purpose: This study aimed to compare two daily disposable lenses to reduce lens-induced discomfort (CLD) among different populations of symptomatic wearers.

Methods: This was a multicenter, crossover, study. Subjects were contact lens wearers reporting CLD.

Prevalence of asymptomatic ocular conditions in subjects with refractive-based symptoms.

Background: This study aims to determine the overall prevalence of ocular conditions in a population from 19 to 64 years old, presenting with refractive-based symptoms only. Results could impact clinical standard of eye care on a similar population.

Methods: This is a retrospective study on patients seen for an eye examination at the Clinique Universitaire de la Vision (CUV), between January 2007 and 2009.

Vascular tortuosities of the upper eyelid: a new clinical finding in fabry patient screening.

Purpose. To report a new clinical finding related to Fabry disease. Methods.

Contribution of soft lenses of various powers to the optics of a piggy-back system on regular corneas.

Purpose: This study aims to report on the measured in vivo contribution of soft lenses of various powers to the optics of a piggyback system (PBS).

Methods: This prospective, non-dispensing clinical study was conducted on regular wearers of contact lenses who showed regular corneal profiles. Subjects were masked to the products used.

Predicting estimates of oxygen transmissibility for scleral lenses.

Background/purpose: Although scleral contact lenses are prescribed with increasing frequency, little is known about their long-term effects on ocular physiology. The main goal of this paper is to predict values of oxygen transmissibility of scleral lens systems by applying the concept of resistors in series to parameters characteristic of current scleral lenses. A second aim is to find the maximal lens and post-lens tear layer thickness combinations above which hypoxia-induced corneal swelling would be found.

Evaluation of Sodium Hyaluronate Lubricating Drops Used before Insertion of Contact Lenses on Symptomatology, Severity, and Intensity of Ocular Dryness.

Purpose. This study aimed to evaluate outcomes from the use of a sodium hyaluronate (SH)-based comfort drop, instilled before the insertion of contact lenses, in a population of symptomatic contact lens wearers. Methods.