Publications by authors named "Lang-hui Zhang"
[Oral Mucosal Diffuse Large B-cell Lymphoma Caused by Long-term Oral Methotrexate:Report of One Case].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
June 2021
Article Synopsis
- * The study analyzes the clinical features, diagnosis, treatment, and prognosis of DLBCL associated with MTX therapy, aiming to enhance awareness among healthcare professionals about this condition.
- * Findings from this case provide new insights that could aid in the clinical diagnosis and management of DLBCL linked to methotrexate in similar patients.
MicroRNAs (miRs) are often located in genomic breakpoint regions and are hypothesized to be important regulators involved in the regulation of critical cell processes, including cell apoptosis, proliferation and differentiation. miR-299 has been reported to be upregulated in acute promyelocytic leukemia (APL); however, the function and mechanistic role of miR-299 in APL remains unknown. The present study demonstrated mir-299 significantly induced cell growth and cell cycle progression at the G1/S transition in APL cells.
View Article and Find Full Text PDF[Expression and Clinical Significance of Bmi-1 and P14 in Extranodal NK/T-cell Lymphoma].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2015
Article Synopsis
- The study investigates the roles of Bmi-1 and P14 proteins in extranodal NK/T-cell lymphoma (ENKTCL) by comparing their expression in lymphoma tissues versus normal lymph nodes.
- Results show that Bmi-1 levels are significantly higher in ENKTCL tissues, while P14 levels are lower, with Bmi-1 expression being linked to the clinical stage of the disease.
- There is a negative correlation between Bmi-1 and P14, suggesting that high levels of Bmi-1 may inhibit P14, potentially influencing the development and progression of ENKTCL.
[Construction of recombinant adenovirus vector containing human survivin gene and its expression in dendritic cells].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2006
The study was aimed to construct the recombinant adenovirus vectors containing human survivin gene, and to investigate their expression in transfected dendritic cells. Full length cDNA encoding survivin was obtained by PCR amplification from plasmid pcDNA3.0-survivin.
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