Group-Based Trajectory Modeling of Platelet in Patients with Aplastic Anemia: A Study Based on the MIMIC Database.

Background: Platelets are the main components supporting coagulation and hemostasis. Nevertheless, no sufficient research has been done on how variations in platelet counts during hospital stays affect aplastic anemia (AA) patients' prognoses.

Objective: This study proposes to evaluate the association between alterations in platelet levels and illness risk in patients with AA using group-based trajectory modeling (GBTM).

Polaron formation by electron polarization in two-dimensional transition metal halides.

An electron in solid can be dressed by the lattice distortions of surroundings, forming a localized composite quasiparticle called small polaron, whose formation has been customarily attributed to the electron-phonon couplings that the ion polarization traps the excess electron. Here we present a theory of electron-polarization induced small polaron, in which the carrier localization happens spontaneously and drives subsequent ion relaxation. This mechanism of polaron formation is qualitatively different than the Mott-Stoneham picture in that there is no need to overcome a kinetic barrier for the carrier to self-trap to form a polaron.

Multi-target regulatory effects of rhaponticin in a rat model of hepatic fibrosis revealed by non-targeted metabolomics.

Introduction: Hepatic fibrosis (HF), a progressive chronic liver disease, is a serious threat to global public health. The lack of preventive and therapeutic strategies has created an urgent need for effective anti-fibrosis agents. There is growing evidence that natural products might provide safe and effective interventions for HF.

Flowering in the Northern Hemisphere is delayed by frost after leaf-out.

Late spring frosts, occurring after spring phenological events, pose a dire threat to tree growth and forest productivity. With climate warming, earlier spring phenological events have become increasingly common and led to plants experiencing more frequent and severe frost damage. However, the effect of late spring frosts after leaf-out on subsequent flowering phenology in woody species remains unknown.

Revealing the Interlayer Interaction Forces in 2D Graphene Materials by Graphene-Wrapped Nanoprobe.

Understanding the interlayer interaction between 2D layered structures is critical for the construction of various micro- and nanoscale functional devices. However, both the normal and the tangential interlayer interactions between 2D layered materials have rarely been studied simultaneously. In this work, an immersion and lift-up method is proposed to wrap a layer of graphene flakes onto a plasma-pretreated atomic force microscopy (AFM) nanoprobe for the measurements of interaction forces by AFM.

Phylogenomics resolves a 100-year-old debate regarding the evolutionary history of caddisflies (Insecta: Trichoptera).

Trichoptera (caddisfly) phylogeny provides an interesting example of aquatic insect evolution, with rich ecological diversification, especially for underwater architecture. Trichoptera provide numerous critical ecosystem services and are also one of the most important groups of aquatic insects for assessing water quality. The phylogenetic relationships of Trichoptera have been debated for nearly a century.

All-Optical Control of Ultrafast Switching between the Hybridized Plasmonic Fields of Au Nanorod Dimer in fs-nm Scale with Dispersed Femtosecond Laser.

With the increasing demand for ultrafast communication and information processing in future optical chips, arbitrary manipulation of electromagnetic fields in the femtosecond-nanometer spatiotemporal scale has attracted great attention in integrated optics. Manipulation of the nanoscale light field in the real femtosecond temporal domain is challenging work. Here, we have demonstrated all-optical control of ultrafast switching between the hybridized plasmonic fields of a Au nanorod dimer in the fs-nm scale using a dispersed femtosecond laser and revealed the transformation process with ultrahigh spatiotemporal resolved technology via the combination of a pump-probe technique and photoemission electron microscopy (PEEM).

Associations of Handgrip Strength Weakness and Asymmetry with Lower Cognitive Function: Results from the National Health and Nutrition Examination Survey (2011-2014).

Background: The joint associations of handgrip strength (HGS) weakness and asymmetry with cognitive decline remain understudied in older adults.

Objective: To investigate the associations between HGS weakness, asymmetry, and lower cognitive function in a nationally representative sample of older Americans.

Methods: This cross-sectional study utilized data from the National Health and Nutrition Examination Survey 2011-2014.

Increased Angio-Derived Index of Microcirculatory Resistance Within a Timeframe of 30-60 days After COVID-19 Infection.

Background And Objectives: Chest pain is a relatively long-term symptom that commonly occurs in patients who have contracted COVID-19. The reasons for these symptoms remain unclear, with coronary microvascular dysfunction (CMD) emerging as a potential factor. This study aimed to assess the presence of CMD in these patients by measuring the angio-derived index of microcirculatory resistance (AMR).

Construction of a nursing assessment framework for patients in anaesthesia recovery period: A modified Delphi study.

Aim: To construct a nursing assessment framework for patients in anaesthesia recovery period.

Design: A three-round modified Delphi method was employed to capture the consensus of 22 panellists.

Methods: The initial items in the nursing assessment framework for patients in anaesthesia recovery period were developed based on the mini-clinical evaluation exercise (mini-CEX).

Chromosome-scale genome assemblies of Himalopsyche anomala and Eubasilissa splendida (Insecta: Trichoptera).

Trichoptera is one of the most evolutionarily successful aquatic insect lineages and is highly valued value in adaptive evolution research. This study presents the chromosome-level genome assemblies of Himalopsyche anomala and Eubasilissa splendida achieved using PacBio, Illumina, and Hi-C sequencing. For H.

Seven new species and four new records of Psychomyiidae (Insecta, Trichoptera) from China.

Seven new species of the family Psychomyiidae Walker, 1852 are described and illustrated from China; they are , , , , , , and The genus is reported for the first time from mainland China. In addition, four psychomyiids are found to be new to the Chinese caddis fauna: Malicky & Chantaramongkol, 1993; Malicky, 1979; Malicky & Chantaramongkol, 1993; and Johanson & Oláh, 2008. Moreover, Li, Qiu & Morse, 2021 is reviewed and synonymized with Malicky, 2020.

Deciphering driver regulators of cell fate decisions from single-cell transcriptomics data with CEFCON.

Single-cell technologies enable the dynamic analyses of cell fate mapping. However, capturing the gene regulatory relationships and identifying the driver factors that control cell fate decisions are still challenging. We present CEFCON, a network-based framework that first uses a graph neural network with attention mechanism to infer a cell-lineage-specific gene regulatory network (GRN) from single-cell RNA-sequencing data, and then models cell fate dynamics through network control theory to identify driver regulators and the associated gene modules, revealing their critical biological processes related to cell states.

[Levels and Clinical Significances of sPD-1 and sPD-L1 in Peripheral Blood of Lymphoma Patients].

Objective: To observe the levels of soluble programmed cell death protein 1 (sPD-1) and soluble programmed cell death ligand 1 (sPD-L1) in peripheral blood of lymphoma patients, and reveal their clinical significances.

Methods: The peripheral blood specimens and clinical data of 64 newly diagnosed lymphoma patients and 30 healthy volunteers were collected. The levels of sPD-1 and sPD-L1 were detected by enzyme-linked immunosorbent assay (ELISA), and their correlations with clinical characteristics of the patients including pathological type, stage, lactate dehydrogenase (LDH) level, T cell subsets were analyzed.

Impact of the geometry of the excitation structure on optical skyrmion.

Optical skyrmions have attracted great attention for the potential applications in novel information storage and communication. It is of great significance to get insight into the generation of optical skyrmions by surface waves. Here, we have paid greater emphasis on the influence of the geometry of the coupling structure on the formation of optical skyrmions.

High spatiotemporal resolved imaging of ultrafast control of nondiffracting surface plasmon polaritons.

Nondiffracting Bessel surface plasmon polariton (SPP) beams, which have unique self-healing, non-divergence, and linear transmission properties, have charming applications in plasmonic devices and on-chip interconnection circuits. Here we first realize, to the best of our knowledge, the ultrafast control and imaging of the Bessel SPP pulse on the nano-femto scale in the experiment. We demonstrate ultrafast control of Bessel SPP pulse switching by controlling the instantaneous polarization state of the excitation light.

Growth of self-integrated atomic quantum wires and junctions of a Mott semiconductor.

Continued advances in quantum technologies rely on producing nanometer-scale wires. Although several state-of-the-art nanolithographic technologies and bottom-up synthesis processes have been used to engineer these wires, critical challenges remain in growing uniform atomic-scale crystalline wires and constructing their network structures. Here, we discover a simple method to fabricate atomic-scale wires with various arrangements, including stripes, X-junctions, Y-junctions, and nanorings.

Five new species of Tinodes (Trichoptera: Psychomyiidae) from China.

Five new species of genus Tinodes Curtis 1834 from China are described, illustrated, and diagnosed based on distinctive characters of male genitalia, including Tinodes falcata n. sp., T.

Comprehensive analysis of the FOXA1-related ceRNA network and identification of the MAGI2-AS3/DUSP2 axis as a prognostic biomarker in prostate cancer.

Background: Prostate cancer (PCa) is the second most common cause of cancer-related deaths in American men. Even though increasing evidence has disclosed the competitive endogenous RNA (ceRNA) regulatory networks among cancers, the complexity and behavior characteristics of the ceRNA network in PCa remain unclear. Our study aimed to investigate the forkhead box A1 (FOXA1)-related ceRNA regulatory network and ascertain potential prognostic markers associated with PCa.

Four New Species of the Genus (Trichoptera: Psychomyiidae) from China Inferred from Morphology and DNA Barcodes.

Four new species of the genus Kimmins, 1955 from China are described, illustrated, and diagnosed based on male genitalia: sp. nov. from Hainan, sp.

New species of the genus Curtis, 1834 (Trichoptera, Molannidae) in China inferred from morphology and DNA barcodes.

The male adult of Ge, Peng & Sun is described and illustrated based on material collected in Si-chuan, China. It could be diagnosed by the subtriangular superior appendages when viewed dorsally, and by the mesal appendages each having a slender thorn and inferior appendages with a tiny inner process. Based on morphology of genitalia, we provide a dichotomous key to adult males of from the Oriental region.

Molecular characterization of extracellular vesicles derived from follicular fluid of women with and without PCOS: integrating analysis of differential miRNAs and proteins reveals vital molecules involving in PCOS.

Purpose: To elucidate the characterization of extracellular vesicles (EVs) in the follicular fluid-derived extracellular vesicles (FF-EVs) and discover critical molecules and signaling pathways associating with the etiology and pathobiology of PCOS, the differentially expressed miRNAs (DEmiRNAs) and differentially expressed proteins profiles (DEPs) were initially explored and combinedly analyzed.

Methods: First, the miRNA and protein expression profiles of FF-EVs in PCOS patients and control patients were compared by RNA-sequencing and tandem mass tagging (TMT) proteomic methods. Subsequently, Gene Ontology and the Kyoto Encyclopedia of Genes and Genomes were used to analyze the biological function of target genes of DEmiRNAs and DEPs.

New Mitogenome Features of Philopotamidae (Insecta: Trichoptera) with Two New Species of .

A total of 14 individuals of Philopotamidae, from China, were examined. Six species in four genera, including two new species of the genus , were recognized. Their barcode sequences were extracted, mitogenomes were sequenced, assembled and analyzed.