Ultrasmall FeS Nanoparticles-Decorated Carbon Spheres with Laser-Mediated Ferrous Ion Release for Antibacterial Therapy.

Recent progress in nanotechnology and the ancient use of sulfur in treating dermatological disorders have promoted the development of nano-sulfides for antimicrobial applications. However, the variable valences and abundant forms of nano-sulfides have complicated investigations on their antibacterial activity. Here, carbon nanospheres (CNSs) with decoration of ultrasmall FeS nanoparticles (CNSs@FeS ) is synthesized, and their antibacterial ability and mechanism are explored.

Photolysis of methicillin-resistant using Cu-doped carbon spheres.

Developing alternative treatment strategies against methicillin-resistant Staphylococcus aureus (MRSA) infections is a challenge but could have many potential applications. In this paper, we developed a novel approach to eradicate MRSA through photolysis of the staphyloxanthin (STX) pigment found within the MRSA membranes and intracellular molecules (e.g.

Using a visible light-triggered pH switch to activate nanozymes for antibacterial treatment.

Here, we develop a visible light-triggered platform to activate the biomimetic activity of CuS nanoparticles by incorporating a photoacid generator. Under visible-light illumination, the remarkable pH decrease, caused by the intramolecular photoreaction of the photoacid generator, activates the peroxidase-like activity of the CuS nanoparticles. This visible light-triggered pH switch meets the antibacterial demands of peroxidase mimics perfectly in bacteria-infected wounds.

Copper/Carbon Hybrid Nanozyme: Tuning Catalytic Activity by the Copper State for Antibacterial Therapy.

Metal-carbon hybrid materials have shown promise as potential enzyme mimetics for antibacterial therapy; however, the effects of metal states and corresponding antibacterial mechanisms are largely unknown. Here, two kinds of copper/carbon nanozymes were designed, with tuned copper states from Cu to Cu. Results revealed that the copper/carbon nanozymes exhibited copper state-dependent peroxidase-, catalase-, and superoxide dismutase-like activities.