Publications by authors named "Landon S Polakof"
Background: Serum cluster of differentiation 64 (CD64) has emerged as a diagnostic test for musculoskeletal infections. The purpose of this study was to evaluate the utility of serum CD64 in diagnosing periprosthetic joint infections (PJIs) compared to conventional markers like white blood count (WBC), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and interleukin-6 (IL-6).
Methods: A prospective case-control study on patients undergoing revision hip or knee arthroplasty surgery >6 weeks after their index surgery was performed at a single institution.
Background: Although 2-stage exchange arthroplasty, consisting of temporary insertion of an antibiotic-impregnated cement spacer (AICS), is considered the standard of care for chronic periprosthetic joint infection (PJI) in total hip arthroplasty (THA), a consensus on the AICS design has not yet been established. Ceramic-on-polyethylene AICSs (Poly-AICS) are theorized to cause less pain and better function than cement-on-bone AICS (CemB-AICS) but use non-antibiotic-impregnated components that may harbor bacteria. This study evaluates the impact of spacer design on infection-free survivorship following THA reimplantation as well as pain and function during the interim AICS stage.
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- The study investigates the effectiveness of perioperative fascia iliaca regional anesthesia (FIRA) in reducing pain for hip fracture patients, aiming to identify which types of fractures and surgeries gain the most benefit.
- Conducted at a Level 1 trauma center, the research compared 949 patients over 60 receiving FIRA with a historical control group not receiving the treatment, assessing morphine milliequivalents (MME) used during hospitalization.
- Findings indicate that FIRA significantly reduced MME consumption preoperatively for femoral neck fractures and postoperatively for both femoral neck and intertrochanteric fractures, as well as for patients undergoing certain surgical procedures like cephalomedullary nail fixation
Article Synopsis
- Fascia iliaca nerve blocks, either single-shot or continuous, were studied for their effect on pain relief and opioid consumption in geriatric patients with hip fractures.
- A total of 107 patients were analyzed, and results showed no significant differences in opioid milligram equivalent (MME) consumption or visual analog scale (VAS) pain scores between the two methods at various time points.
- Both methods led to a significant reduction in hourly opioid consumption post-block, but secondary outcomes like length of hospital stay and readmission rates were also similar between the two approaches.
Article Synopsis
- FIBs help manage pain in older hip fracture patients and reduce opioid use before surgery.
- Delays in administering these blocks negatively impact pain control and recovery.
- Faster TTB leads to lower opioid consumption, reduced pain levels, and shorter hospital stays.
Background: A hamstring autograft is commonly used in anterior cruciate ligament (ACL) reconstruction (ACLR); however, there is evidence to suggest that the tendons harvested may contribute to medial knee instability.
Hypothesis: We tested the hypothesis that the gracilis (G) and semitendinosus (ST) tendons significantly contribute to sagittal, coronal, and/or rotational knee stability in the setting of ACLR with a concurrent partial medial collateral ligament (MCL) injury.
Study Design: Controlled laboratory study.