Increased Insular Functional Connectivity During Repetitive Negative Thinking in Major Depression and Healthy Volunteers.

Background: Repetitive negative thinking (RNT) in major depressive disorder (MDD) involves persistent focus on negative self-related experiences. Resting-state fMRI shows that the functional connectivity (FC) between the insula and the superior temporal sulcus is critical to RNT intensity. This study examines how insular FC patterns differ between resting-state and RNT-induction in MDD and healthy participants (HC).

The sea anchor technique: a novel method to aid in stent-assisted embolization of giant cerebral aneurysms.

Endovascular navigation past some large or giant intracranial aneurysms for the purpose of stent deployment can be difficult. Some of these lesions have a morphology which compels the operator to navigate through the aneurysm dome in order to gain distal access, a step which requires straightening of the delivery microcatheter before a stent can be deployed. In most patients this can be achieved by simply retracting the microcatheter and reducing the loop within the aneurysm.

Skull fractures through parietal foramina: report of two cases.

Enlarged parietal foramina are related to a condition in which defective intramembranous ossification of the parietal bones results in enlargement of the normal foramina. Although generally believed to be a benign variant, scalp defects, seizures, and structural brain abnormalities have been reported in a small percentage of affected patients. These 2 cases now present evidence that parietal foramina constitute structural weak spots in the calvarium that may potentially increase risk of skull fracture after trauma.