Properties of several glycidyl methacrylate-triallyl isocyanurate based affinity adsorbents for removing circulating immune complexes.

Biocompatible affinity adsorbents prepared from macroporous glycidyl methacrylate-triallyl isocyanurate copolymer (GT) has been used for removing circulating immune complexes (CICs). In this work, adsorption of circulating immune complexes on GT-based affinity adsorbents has been studied by using batch and hemoperfusion studies. In batch mode, the equilibrium adsorption level was determined to be a function of the contact time, temperature, initial CIC concentration and adsorbent dosage.