Hypoproteinemia does not alter plasma volume expansion in response to a 0.9% saline bolus in awake sheep.

Objective: To test the hypothesis that hypoproteinemia reduces plasma volume expansion produced by a bolus of crystalloid solution given to awake sheep.

Design: Prospective and observational.

Setting: Laboratory.

Influence of rate and volume of infusion on the kinetics of 0.9% saline and 7.5% saline/6.0% dextran 70 in sheep.

Unlabelled: We examined whether volume kinetic variables obtained during infusion of a short bolus of 0.9% saline (NS) or 7.5% saline/6.