Incidence and Geographical Variability of Pediatric Inflammatory Bowel Disease in Croatia: Data From the Croatian National Registry for Children With Inflammatory Bowel Disease.

The aim of this study was to determine the annual incidence and geographic distribution of pediatric inflammatory bowel disease (IBD) in Croatia. This is a prospective, cohort, multicenter observational study based on the data obtained from the Croatian national registry for children with IBD. Children and adolescents younger than 18 years diagnosed with IBD, in time period between June 1, 2016, and May 31, 2017, were recruited.

IBD phenotype at diagnosis, and early disease-course in pediatric patients in Croatia: data from the Croatian national registry.

Background: Pediatric inflammatory bowel disease (IBD) presents with extensive phenotype. The aim of this study was to determine the phenotype of pediatric IBD patients in Croatia at diagnosis and follow-up.

Methods: Children were prospectively recruited into Croatian IBD national registry.

Lactobacillus reuteri DSM 17938 in the Treatment of Functional Abdominal Pain in Children: RCT Study.

Objectives: Beneficial therapeutic effect of probiotics has been reported in children with the irritable bowel syndrome (IBS) but not consistently in other functional abdominal pain-related disorders. The aim of the present study was to investigate the effect of Lactobacillus reuteri DSM 17938 in the treatment of functional abdominal pain (FAP) and IBS in children.

Methods: Children (age 4-18 years) referred to pediatric gastroenterologist at Children's Hospital Zagreb from May 2012 to December 2014, diagnosed as FAP or IBS, were randomized to receive L reuteri DSM 17938 10⁸ CFU daily or placebo.

THE ROLE OF TRANSITION CLINIC IN THE HEALTH CARE OF ADOLESCENTS WITH CHRONIC INFLAMMATORY BOWEL DISEASE.

Inflammatory bowel disease (IBD) is a chronic disease of the digestive system that occurs in one third of cases in childhood and adolescence. In the majority of patients IBD persists and relapses more or less frequently during their whole life and therefore pediatric patients, at some point, are transferred to the adult health care where autonomy and responsibility are required. However, adolescents with infl ammatory bowel disease are mostly insuffi ciently competent in respect to disease specifi c knowledge and self-management skills what can lead to poor disease outcome.