The Effectiveness of Probiotics on Oral Health During Adult Orthodontic Treatment With Fixed Appliances: A Two-Arm Parallel-Group Randomized Controlled Clinical Trial.

Background And Objectives: Fixed orthodontic appliances interfere with daily oral care procedures, causing more plaque accumulation and thus increasing the risk of periodontal diseases. Probiotics have been suggested to maintain oral health using beneficial bacteria. However, the evidence to determine the clinical benefits of probiotics as a supplement to oral health in orthodontic patients is still insufficient.