Strontium nitrate-dopped zinc oxide-loaded alginate gels with gentamicin for improved wound healing.

Wound dressing development is an area of active research. Traditional dressings lack antibacterial activity, biocompatibility, and tissue regeneration. Alginate is a heavily investigated polymer employed as wound dressings and can be combined with a wide range of additives.

A novel HEMA copolymer hydrogel with antifouling and anti-inflammatory activity as a promising medical device coating layer to prevent microbial adhesion.

Compared to antimicrobial agents, anti-adhesive surfaces can reduce bacteria adhesion and biofilm formation in catheters, providing better selectivity, efficiency, and device life span. In this research, novel anionic surface biomaterials were created and tested to reduce microbial adhesion and colonization in medical device coating. Maleic anhydride (MA) was polymerized with 2-HEMA in varying amounts to produce a p(HEMA--MA) hydrogel copolymer.