Same-day single-dose large-volume split-dose regimens of polyethylene glycol for bowel preparation: A systematic review and meta-analysis.

Background: Split-dose regimens (SpDs) of 4 L of polyethylene glycol (PEG) have been established as the "gold standard" for bowel preparation; however, its use is limited by the large volumes of fluids required and sleep disturbance associated with night doses. Meanwhile, the same-day single-dose regimens (SSDs) of PEG has been recommended as an alternative; however, its superiority compared to other regimens is a matter of debate.

Aim: To compare the efficacy and tolerability between SSDs and large-volume SpDs PEG for bowel preparation.