Publications by authors named "Lan-Lan Xiang"
Background: The birth of large-for-gestational-age (LGA) infants is associated with many short-term adverse pregnancy outcomes. It has been observed that the proportion of LGA infants born to pregnant women with gestational diabetes mellitus (GDM) is significantly higher than that born to healthy pregnant women. However, traditional methods for the diagnosis of LGA have limitations.
View Article and Find Full Text PDFPurpose: The aim of this study was to evaluate the relationship among inflammatory cytokines including hypersensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6), glycated hemoglobin A1c (HbA1c), and platelet distribution width (PDW) in women with gestational diabetes mellitus (GDM).
Methods: Data on 191 pregnant women (96 women with GDM; 95 healthy controls) were extracted from routine prenatal examination records in Nanjing, China. Fasting concentrations of hs-CRP, IL-6, HbA1c, blood cell indices, and glucose at 24-28th gestational weeks were determined.
Article Synopsis
- Gestational diabetes mellitus (GDM) is a common pregnancy-related metabolic disorder that can have harmful effects on both mothers and their babies, but its causes and mechanisms are not fully understood.
- Metabolomics, the study of small molecular metabolites, can help track changes in metabolism during pregnancy, aiding in the identification of diagnostic biomarkers and the evaluation of treatment effectiveness.
- This review discusses the methods and advancements in metabolomics research related to GDM, aiming to highlight knowledge gaps and guide future studies in the field.