Publications by authors named "Lan Sheng"

The interaction between ultrafast, tightly focused lasers and materials has garnered significant interest owing to its distinctive properties. In this study, we present a versatile methodology for the fabrication of tunable plasmonic nanostructures by employing a disordered gold nanoisland-dielectric-metal configuration, achieved through femtosecond laser printing. By reshaping the gold nanoislands and reconfiguring them into nanograting-like structures, the orientation of these nanostructures is influenced by the polarization of the femtosecond laser light, leading to controllable plasmon resonance and polarization-sensitive color display.

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Nonlinear emission phenomena observed in transition metal dichalcogenides (TMDCs) have significantly advanced the development of robust nonlinear optical sources within two-dimensional materials. However, the intrinsic emission characteristics of TMDCs are inherently dependent on the specific material, which constrains their tunability for practical applications. In this study, we propose a strategy for the selective enhancement and modification of second-harmonic generation (SHG) emission in a multilayer WS flake through the implementation of a silicon (Si)-based circular Bragg grating (CBG) structure positioned on an Au/SiO substrate.

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Two-dimensional (2D) transition metal dichalcogenide (TMDC) monolayers are promising materials for light-emitting devices due to their excellent electric and optical properties. However, defects are inevitably introduced in the fabrication of TMDC monolayers, significantly influencing their emission properties. Although photoluminescence (PL) is considered as an effective tool for investigating the defects in TMDC monolayers.

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Under the influence of the polarization effect, the background stray light of the weak starlight simulator and the polarization state of the simulated target star point are doped with each other, so it is difficult to achieve accurate suppression of polarized stray light. In this paper, the mechanism of background stray light induced by the optical engine in a weak starlight simulation device is analyzed, and the principle of mutual doping between stray light and simulated target starlight polarization state is studied. The correlation model of polarization parameters, point source transmittal, and simulated target magnitude was established, and the optimization process of polarization effect was constructed to achieve accurate suppression of polarized stray light in the star map background.

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In the weak star simulator, the background stray light of the self-excited star image and the simulated target star light are mixed with each other, which is difficult to separate and reduces the simulation accuracy of the star position. Therefore, based on the polarized light tracing method, this paper explores the induction mechanism of the polarization effect of the weak star simulator on the background stray light field of the star map, and proposes a polarization balance optimization method for the beam splitter film. At the same time, the mapping model of star position simulation accuracy, polarization parameters of beam splitter and polarization stray light suppression degree is established.

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Article Synopsis
  • - Research on luminescence in crystalline silicon (c-Si) has been difficult since lasers were invented in the field of photonics.
  • - Recent improvements in nanofabrication techniques have contributed significantly to this research.
  • - New studies into optical resonance and carrier dynamics have led to successful and efficient luminescence in c-Si.
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Article Synopsis
  • The study discusses a new method to convert electric dipole (ED) emission into magnetic dipole (MD) emission by coupling an ED emitter with a silicon nanoparticle that has strong MD resonance.
  • This transformation results in an artificially created MD source with a high purity factor of up to 99%, showcasing magnetic-type emission patterns through experimental measurements.
  • The research not only provides insights into ideal magnetic dipole emission from nonmagnetic emitters but also holds promise for advancements in magnetic optical nanosources and various photonic applications.
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Polarization plays a paramount role in scaling the optical network capacity. Anisotropic two-dimensional (2D) materials offer opportunities to exploit optical polarization-sensitive responses in various photonic and optoelectronic applications. However, the exploration of optical anisotropy in fiber in-line devices, critical for ultrafast pulse generation and modulation, remains limited.

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Optical pulling provides a new degree of freedom in optical manipulation. It is generally believed that long-range optical pulling forces cannot be generated by the gradient of the incident field. Here, we theoretically propose and numerically demonstrate the realization of a long-range optical pulling force stemming from a self-induced gradient field in the manipulated object.

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Article Synopsis
  • Cuproptosis is a newly identified type of programmed cell death that is linked to neuroendocrine tumors and metabolism, but its specific role in Hepatocellular carcinoma (HCC) has not been thoroughly explored.
  • Researchers used bioinformatics analyses to construct a prognostic gene model and a competing endogenous RNA (ceRNA) network to examine the relationship between cuproptosis-related genes (CRGs) and various clinical factors in HCC patients.
  • The study identified a 3-gene signature associated with CRGs that effectively predicts HCC patient prognosis, revealing correlations with immune factors and suggesting potential new biomarkers and treatment targets.
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Nonrigid registration of medical images is formulated usually as an optimization problem with the aim of seeking out the deformation field between a referential-moving image pair. During the past several years, advances have been achieved in the convolutional neural network (CNN)-based registration of images, whose performance was superior to most conventional methods. More lately, the long-range spatial correlations in images have been learned by incorporating an attention-based model into the transformer network.

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The construction of type-II or S-scheme heterojunctions can effectively accelerate the directional migration of charge carriers and inhibit the recombination of electron-hole pairs to improve the catalytic performance of the composite catalyst; therefore, the construction and formation mechanism of a heterojunction are worth further investigation. Herein, CuO@Cu(SO)(OH)·HO core-shell polyhedral heterojunctions were fabricated via in situ etching CuO with octahedral, cuboctahedral, and cubic shapes by sodium thiosulfate (NaSO). CuO@Cu(SO)(OH)·HO polyhedral heterojunctions demonstrated obviously enhanced sterilization and degradation performance than the corresponding single CuO polyhedra and Cu(SO)(OH)·HO.

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Supramolecular polymer networks (SPNs) based on pillar[n]arene are widely studied and it is known that evolution from linear polymers to SPNs occurs as a progressive process, which is of importance to monitor the detailed morphology throughout the process. Yet, the current reports related to that distinction by employing fluorescence approach have realized confined success, it still remains a challenge to distinguish the various states visually. Herein, a fluorescent group of the pyrene benzohydrazonate-based (PBHZ-based) derivative is introduced into the pillar[5]arene based SPNs gained from host-guest recognition, enabling the visual monitoring during the formation of SPNs.

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Background: Previous studies have revealed the significant roles of SHC SH2 domain-binding protein 1 (SHCBP1) in occurrence and progression of cancers, but there is no pan-cancer analysis of SHCBP1.

Methods: In this study, we explored the potential carcinogenic role of SHCBP1 across 33 tumors from the TCGA and GTEx databases. We investigated SHCBP1 expression, prognosis, genetic alterations, tumor mutational burden (TMB) score, microsatellite instability (MSI) and tumor microenvironment from TIMER2, GEPIA2, UALCAN and cBioPortal databases.

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Recent studies have indicated that pyroptosis may participate in the regulation of tumorigenesis and immune microenvironment. However, the role of pyroptosis-related genes (PRGs) in pancreatic adenocarcinoma (PAAD) remains unclear. Through multiple bioinformatics analysis, we constructed a prognostic gene model and competing endogenous RNA network.

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In this study, the photothermal effect and up-conversion florescence imaging effect of gold nanobipyramids in liver cancer cells are investigated theoretically and experimentally to explore the photothermal ablation tumor therapy with higher photothermal conversion efficiency, shorter laser action time, smaller action range and lower laser power. The small-size gold nanobipyramids with good biocompatibility and infrared absorption peak located in the first biological window are synthesized. Femtosecond laser is focused on the nanobipyramids clusters in cells and the cells die after being irradiated for 20 s at a power as low as 3 mW.

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Background: Hepatocellular carcinoma (HCC) is a major public health problem in humans. The imbalance of mitochondrial function has been discovered to be closely related to the development of cancer recently. However, the role of mitochondrial-related genes in HCC remains unclear.

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Background: Hepatocellular carcinoma (HCC) is a major human health concern. Increasing evidence has demonstrated that ubiquitin ligase E4B (UBE4B) may be involved in the occurrence and development of various human cancers and may affect prognosis. However, the specific role and mechanism of UBE4B in HCC is unclear.

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The detection and monitoring of ultralow humidity (<100 ppm) are critical in many important industries, such as high-tech manufacturing, scientific research, and aerospace. However, the development of ppm level humidity sensors with portability, low cost, and ease of regeneration remains a significant challenge. Herein, an innovative "enzyme-like" construction strategy is proposed to address this problem by employing suitable molecular-level humidity-sensitive units and chemically constructing a multilevel spatial synergistic sensitization microenvironment around it.

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Polystyrene (PS) is generally considered as a passive optical material that is transparent to light with wavelengths longer than 300 nm. In practice, PS micro- and nanospheres with uniform sizes are usually used to build photonic crystals based on self-assembly mechanism. Here, we demonstrate experimentally that PS microspheres supporting whispery gallery modes can be transformed into multimode light sources by laser irradiation.

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Thin-film pervoskite lasers driven by a continuous wave (CW) laser with ultralow thresholds, which is crucial for the development of on-chip electrically driven lasers, have not yet been realized owing to the low excitation power density of the CW laser. Here, we reported the CW-laser-pumped lasing from a thin film of CsPbBr quantum dots (QDs) sandwiched by a SiN and a Ag thin film and mediated by the whispering gallery modes of a SiO microsphere. The stable photoluminescence from CsPbBr QDs with a quantum efficiency of ∼45% is realized by encapsulating with a thin SiN film.

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Article Synopsis
  • Strong plasmon-exciton coupling has been achieved using metallic nanocavities and 2D materials, crucial for applications in nanophotonics and quantum electrodynamics.
  • Researchers have successfully demonstrated the optical control of plasmon-exciton-trion coupling in a dielectric-metal hybrid nanocavity made of silicon nanoparticles, a gold film, and a tungsten disulfide monolayer.
  • By adjusting the laser power, they manipulated the coupling strength from weak to strong, enabling the interaction between excitons and trions, suggesting potential for future nanoscale plasmonic devices.
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The low quantum efficiency of silicon (Si) has been a long-standing challenge for scientists. Although improvement of quantum efficiency has been achieved in porous Si or Si quantum dots, highly efficient Si-based light sources prepared by using the current fabrication technooloy of Si chips are still being pursued. Here, we proposed a strategy, which exploits the intrinsic excitation of carriers at high temperatures, to modify the carrier dynamics in Si nanoparticles.

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Background: Anillin (ANLN) is an actin-binding protein that is essential for cell division and contributes to cell growth and migration. Although previous studies have shown that ANLN is related to carcinogenesis, no pan-cancer analyses of ANLN have been reported. Accordingly, in this study, we evaluated the carcinogenic roles of ANLN in various cancer types using online databases.

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Controlling the upconversion luminescence (UCL) intensity ratio, especially pumped at 808 nm, is of fundamental importance in biological applications due to the water molecules exhibiting low absorption at this excitation wavelength. In this work, a series of β-NaYbF:Er microrods were synthesized by a simple one-pot hydrothermal method and their intense green (545 nm) and red (650 nm) UCL were experimentally investigated based on the single-particle level under the excitation of 808 nm continuous-wave (CW) laser. Interestingly, the competition between the green and red UCL can be observed in highly Yb-doped microcrystals as the excitation intensity gradually increases, which leads to the UCL color changing from green to orange.

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