Tuberindine A, a Truffle Alkaloid with an Unprecedented Skeleton Exhibiting Anti-hyperuricemic Bioactivity.

Tuberindines A and B ( and ), truffle alkaloids with intriguing structures, were isolated from and detected in other truffle species. They appear to arise biosynthetically from amino acid and isosaccharinic units. Compound upregulated the expression of organic anion transporters OAT1 and ABCG2 and significantly exhibited antihyperuricemic bioactivity and , which might support the value of truffles as a dietary supplement.

Anti-inflammatory and analgesic monoterpenoid indole alkaloids of Kopsia officinalis.

Ethnopharmacological Relevance: "Ya gai", an important part of Dai medical theory, is traditionally recognized as an antidote. Kopsia officinalis Tsiang et P. T.

Antioxidant and Cytoprotective Effects of New Diarylheptanoids from .

(Zingiberaceae) has been an important food spice and vegetable in southern China. Fifteen phenolic compounds (-) including three new diarylheptanoids, rhynchanines A-C (-) and one new phenylpropanoid, 4--methylstroside B (), were isolated from rhizomes. The structures of new compounds were elucidated by comprehensive analyses through NMR, HRMS technique, acid hydrolysis, and Mosher's reaction.

Screening and identifying hepatobiliary diseases through deep learning using ocular images: a prospective, multicentre study.

Background: Ocular changes are traditionally associated with only a few hepatobiliary diseases. These changes are non-specific and have a low detection rate, limiting their potential use as clinically independent diagnostic features. Therefore, we aimed to engineer deep learning models to establish associations between ocular features and major hepatobiliary diseases and to advance automated screening and identification of hepatobiliary diseases from ocular images.

Dynamic profile of ocular refraction in pediatric cataract patients after lens surgeries.

Aim: To study the change in ocular refraction in patients with pediatric cataracts (PCs) after lens extraction.

Methods: A total of 1258 patients who were undergoing cataract extraction with/without intraocular lens (IOL) implantation were recruited during preoperative examinations between Jan 2010 and Oct 2013. Patient ages ranged from 1.