A Population-Based Assessment of 24-Hour Ocular Perfusion Pressure Among Patients With Primary Open Angle Glaucoma: The Handan Eye Study.

Purpose: To compare the 24-hour ocular perfusion pressure (OPP) among patients with primary open angle glaucoma (POAG) and those with suspected POAG identified in a population-based study in China.

Methods: Forty-seven patients with POAG and 35 with suspected POAG attended the 24-hour OPP study. Intraocular pressure (IOP) and blood pressure (BP) were measured at 2, 6, and 10 AM and 2, 6, and 10 PM.

Rationale, design, and demographic characteristics of the Handan Offspring Myopia Study.

Purpose: The Handan Offspring Myopia Study (HOMS) aims to investigate the familial associations of myopia between parents and their offspring.

Methods: Children aged 6-18 years, residing in 6 villages where all people aged ≥30 years had participated in The Handan Eye Study in 2006-2007, were selected for the current eye study between March and June 2010. A mobile clinic was set up in the 6 villages for comprehensive eye examinations, including visual acuity, ocular biometry, cycloplegic autorefraction and retinal photography.

Eye care use among rural adults in China: the Handan Eye Study.

Purpose: To assess the use of eye care services in a rural population in North China and to analyze the factors associated with underuse of these services.

Methods: In a cross-sectional population-based study, demographic, health and vision-related information including use of eye care services were determined during a face-to-face interview. A single visit to an eye care provider qualified as "use" of eye care services.

The prevalence of and risk factors associated with pterygium in a rural adult Chinese population: the Handan Eye Study.

Purpose: To describe the prevalence and risk factors for pterygium in a rural adult Chinese population.

Methods: A total of 7557 people aged 30 years and over were randomly selected from 13 villages in a rural county, Yongnian, within Handan district, Hebei Province of China. All eligible subjects were invited to undergo a comprehensive eye examination.

Intraocular pressure and its relationship to ocular and systemic factors in a healthy Chinese rural population: the Handan Eye Study.

Purpose: To describe the distribution of and factors related to intraocular pressure (IOP) in a healthy adult rural Chinese population in northern China.

Methods: The Handan Eye Study is a cross-sectional, population-based study of eye diseases among 6,830 (90.4% response rate) rural Chinese persons aged 30+ years.

Prevalence and associations of cataract in a rural Chinese adult population: the Handan Eye Study.

Background: Cataract remains the leading cause of blindness and visual impairment in the world and in China. However, data on the prevalence of cataract based on standardized lens grading protocols from mainland China are limited. This paper estimated the age- and gender-specific prevalence and risk factor for cataract

Methods: In a population-based Chinese sample, participants underwent a comprehensive ophthalmic examination, including assessment of cortical, nuclear, posterior subcapsular (PSC) and mixed lens opacities from slit-lamp grading using the Lens Opacities Classification System III.

[Assess correlation between bleb morphology at long-term intraocular pressure effect in primary angle-closure glaucoma following trabeculectomy].

Objective: To evaluate the correlation between morphologic appearance of blebs at 3 month and long-term intraocular pressure (IOP) effect in patients with primary angle-closure glaucoma (PACG) after trabeculectomy.

Methods: Multi-centered cases series. Data were collected from 176 patients aged ≥ 40 years with PACG who were participated in a randomized clinical trial that aimed at addressing the efficacy of augmented releasable sutures after trabeculectomy.

[Alteration of anterior chamber and angle structure in eyes with primary angle closure after laser peripheral iridotomy].

Objective: To quantitatively evaluate the long-term changes in anterior segment morphology by using ultrasound biomicroscopy (UBM) after laser peripheral iridotomy (LPI) in eyes with primary angle closure (PAC).

Methods: This was a clinical case series study. A total of 54 eyes with PAC of 31 consecutive patients were enrolled.

[Physical exercise and intraocular pressure].

In the 1960s, it had been observed that physical exercises could reduce the intraocular pressure (IOP) in patients with glaucoma. However, the effect of IOP reduction varied with exercise type and intensity, as well as the duration after exercise. Difference of lowering the IOP in glaucoma patients and healthy people were also observed.

Long-term intraocular pressure fluctuation of primary angle closure disease following laser peripheral iridotomy/iridoplasty.

Background: Many studies indicated that short-term and long-term intraocular pressure (IOP) fluctuations in primary open angle glaucoma patients might lead to glaucomatous progression. However, seldom study has evaluated the long-term fluctuation of IOP in primary chronic angle closure diseases. The objective of this study was to investigate the long-term IOP fluctuation of primary angle closure diseases and its associations following laser peripheral iridotomy (LPI) with or without laser peripheral iridoplasty.

Association of dilated retinal arteriolar caliber with early age-related macular degeneration: the Handan Eye Study.

Background: To identify factors associated with early age-related macular degeneration (AMD) in a rural Chinese population, with emphasis on retinal vessel caliber.

Methods: The study population comprised the 6,830 participants of the Handan Eye Study. All participants underwent digital retinal photography of both eyes.

Prevalence and characteristics of primary angle-closure diseases in a rural adult Chinese population: the Handan Eye Study.

Purpose: To investigate the prevalence and characteristics of primary angle-closure suspect (PACS), primary angle closure (PAC), and primary angle-closure glaucoma (PACG) in a rural population in China.

Methods: In all, 6716 Han Chinese 30 years of age and older (5480 subjects 40 years of age and older) from 13 villages in Handan were randomly selected and completed an ophthalmologic examination, including visual acuity, intraocular pressure (IOP), slit-lamp examination, gonioscopy and stereoscopic photography, and visual field. PACS was defined as present if either eye had the posterior trabecular meshwork not visible for 180° or more on gonioscopy.

Prevalence of primary open angle glaucoma in a rural adult Chinese population: the Handan eye study.

Purpose: To estimate the prevalence and associations of primary open angle glaucoma (POAG) in a rural population of northern China.

Methods: In a rural county in Handan, China, 6716 adults residing in 13 villages were randomly selected and participated in the study. All participants completed a comprehensive eye examination, including intraocular pressure (IOP), slit-lamp examination, and fundus evaluation.

A population-based assessment of 24-hour intraocular pressure among subjects with primary open-angle glaucoma: the handan eye study.

Purpose: To describe the distribution of the 24-hour intraocular pressure (IOP) among subjects with primary open-angle glaucoma (POAG) in a population-based study in north China.

Methods: All untreated POAG patients (n = 66) identified in the Handan Eye Study were invited to attend a follow-up study in which IOP was tested with a Goldmann applanation tonometer at 10 AM, 2 PM, 6 PM, 10 PM, 2 AM, and 6 AM.

Results: Forty-seven subjects with untreated POAG (47/66; 71.

Prevalence of age-related macular degeneration in a rural Chinese population: the Handan Eye Study.

Purpose: To describe the prevalence of age-related degeneration (AMD) in a rural Chinese population and to assess its associations with age, gender, and smoking.

Design: Population-based cross-sectional.

Participants: Persons aged 30+ years, recruited between October 2006 and October 2007, from Yongnian County, Handan, Hebei Province, China.

Risk factors for diabetic retinopathy in a rural Chinese population with type 2 diabetes: the Handan Eye Study.

Purpose: To describe risk factors associated with diabetic retinopathy (DR) in a population-based sample of rural Chinese with type 2 diabetes.

Methods: The Handan Eye Study is a population-based cross-sectional study surveyed 6830 Chinese people aged 30+ years from 13 randomly selected villages in 2006-2007. All participants underwent a standardized interview and extensive examinations including ophthalmologic and systemic conditions.

Prevalence and causes of amblyopia in a rural adult population of Chinese the Handan Eye Study.

Objective: To determine the prevalence of and factors associated with amblyopia in a rural Chinese population.

Design: Population-based, cross-sectional study.

Participants: Six thousand eight hundred thirty Han Chinese aged 30 years or more, recruited from Yongnian County, Handan, Hebei Province, China.

Normal macular thickness measurements using optical coherence tomography in healthy eyes of adult Chinese persons: the Handan Eye Study.

Purpose: To describe macular thickness measured by optical coherence tomography (OCT) in healthy eyes of adult Chinese persons.

Design: Population-based cross-sectional study.

Participants: Chinese adults aged 30+ years who were residents of Handan, North China.

Laser peripheral iridotomy with and without iridoplasty for primary angle-closure glaucoma: 1-year results of a randomized pilot study.

Purpose: To compare the efficacy and safety of laser peripheral iridotomy with or without laser peripheral iridoplasty in the treatment of eyes with synechial primary angle-closure or primary angle-closure glaucoma.

Design: Randomized, controlled clinical trial.

Methods: Consecutive patients older than 40 years with synechial primary angle-closure or primary angle closure glaucoma were recruited.

Retinopathy in persons without diabetes: the Handan Eye Study.

Purpose: To describe the prevalence and associations of retinopathy in a population-based nondiabetic sample of rural Chinese.

Design: Population-based cross-sectional study.

Participants: We included 6830 Han Chinese aged > or =30 years from 13 villages of Yongnian County, Handan City, Hebei Province, China.

Refractive errors in a rural Chinese adult population the Handan eye study.

Purpose: To describe the prevalence of and risk factors for myopia and other refractive errors in a rural, adult, Chinese population.

Design: Population-based, cross-sectional study.

Participants: A clustered, random sampling procedure was used to select 7557 Chinese people aged >or=30 years from Handan, China.

Rationale, design, methodology, and baseline data of a population-based study in rural China: the Handan Eye Study.

Purpose: To describe the rationale, design, methodology and baseline characteristics of the Handan Eye Study (HES), a population-based study to determine the prevalence and impact of visual impairment and major ocular diseases in Chinese adults living in a rural region north China.

Methods: Population-based, cross-sectional study. 6830 Han people aged 30 years and older from 13 villages of Yongnian County, Handan city, Hebei province, China were recruited.

Prevalence of diabetic retinopathy in rural China: the Handan Eye Study.

Purpose: To describe the age- and gender-specific prevalence, characteristics, and severity of diabetic retinopathy (DR) in a rural population in northern China.

Design: A population-based cross-sectional study.

Participants: A total of 6830 Han Chinese aged 30 years and older from 13 villages of Yongnian County, Handan City, Hebei Province, China.

Prevalence and associations of epiretinal membranes in a rural Chinese adult population: the Handan Eye Study.

Purpose: To determine the prevalence and association of epiretinal membranes (ERMs), as assessed by retinal photography and optical coherence tomography (OCT), in a Chinese population.

Methods: The Handan Eye Study is a population-based study of eye disease in rural Chinese aged 30+ years. Eligible residents underwent a detailed ophthalmic examination including retinal photography and Stratus OCT.