Publications by authors named "Lan N L Tu"
Antioxid Redox Signal
October 2013
Article Synopsis
- Researchers are targeting thioredoxin reductase (TrxR) for cancer treatment and aimed to identify effective inhibitors from a diverse set of compounds.
- Despite testing various natural compounds, most exhibited weak TrxR inhibition, highlighting the need for more than just a Michael acceptor moiety for efficacy.
- The study successfully developed new compounds with specific modifications that enhanced TrxR inhibition and correlated with their cancer-fighting potential.
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