Publications by authors named "Lamine Diarra"
Effect of Adding a Six-Week Course of Doxycycline to Intensive Hygiene-Based Care for Improving Lymphedema in a Rural Setting of Mali: A Double-Blind, Randomized Controlled 24-Month Trial.
Yaya I Coulibaly Abdoul F Diabate Moussa Sangare Sekou O Thera Housseini Dolo Ayouba Diarra Lamine Diarra
Am J Trop Med Hyg
October 2024
Article Synopsis
- - Lymphedema (LE), a serious condition resulting from lymphatic filariasis, is primarily treated through limb hygiene and local care, with a study exploring doxycycline's potential benefits.
- - A multicenter trial in Mali tested doxycycline (200 mg/day) against a placebo for 6 weeks in patients with LE stages 1-3, measuring the disease's progression over 24 months.
- - Results showed no significant difference in LE progression between the doxycycline and placebo groups, but both experienced reduced acute adenolymphangitis attacks; doxycycline was well tolerated but not more effective than hygiene alone.
Article Synopsis
- Schistosomiasis is a significant public health issue in Mali, particularly in the Kalabancoro District, which has reported high prevalence rates of urinary (10.83%) and intestinal (50.83%) schistosomiasis.
- A study involving 947 participants found that while 76.1% claimed some awareness of schistosomiasis, a majority did not understand how the disease is transmitted or how to prevent it effectively.
- The findings indicate a need for targeted educational interventions in the Kalabancoro community to address misconceptions and improve prevention and treatment knowledge, which are critical for eliminating the disease.
Lymphatic filariasis (LF) elimination activities started in Mali in 2005 in the most endemic areas and reached countrywide coverage in 2009. In 2004, the district of Bamako was endemic for LF with a prevalence of 1.5%.
View Article and Find Full Text PDFBackground: In 2004, Mali implemented mass drug administration (MDA) aimed at controlling schistosomiasis and soil-transmitted helminths. Despite several rounds of MDA, the health district of Bankass reported low coverage (64.8%) for praziquantel and albendazole in 2017, meaning that this district was still facing challenges in accomplishing the targeted 75% coverage.
View Article and Find Full Text PDF