Targeted temperature management using the "Esophageal Cooling Device" after cardiac arrest (the COOL study): A feasibility and safety study.

Background: Targeted temperature management (TTM) between 32 and 36°C is recommended after out-of-hospital cardiac arrest (OHCA). We aimed to assess the feasibility and safety of the "Esophageal Cooling Device" (ECD) in performing TTM.

Patients And Methods: This single-centre, prospective, interventional study included 17 comatose OHCA patients.

Parental origin of the X-chromosome does not influence growth hormone treatment effect in Turner syndrome.

Context: The parental origin of the intact X-chromosome has been reported to affect phenotype and response to GH treatment in Turner syndrome (TS).

Objective: Our objective was to evaluate the influence of the parental origin of the X-chromosome on body growth and GH treatment effect in TS.

Design And Setting: We conducted a population-based cohort study of TS patients previously treated with GH.