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Publications by authors named "Lamees Mohamed Fathi"

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CXC Chemokine Receptor Type 5 Gene Polymorphisms in a Cohort of Egyptian Patients with Diffuse Large B-Cell Lymphoma.
Manal Mohamed Makhlouf Eman Roshdy Radwan Ola Mohamed Khorshed Lamees Mohamed Fathi Manal Mohamed Elmasry

Pathobiology

October 2021

Background: The chemokine receptor CXCR5 is selectively expressed on B cells; it is involved in lymphocyte homing and the development of normal lymphoid tissue. Its principle ligand is CXCL13 or B lymphocyte chemoattractant. Three polymorphisms in the CXCR5 gene, rs148351692 C/G, rs6421571 C/T, and rs78440425 G/A, have been identified.

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Synopsis of recent research by authors named "Lamees Mohamed Fathi"

  • - Lamees Mohamed Fathi's research primarily focuses on the genetic factors influencing lymphocyte behavior in patients with Diffuse Large B-Cell Lymphoma (DLBCL), particularly through the study of chemokine receptor polymorphisms.
  • - The 2021 article examines three specific polymorphisms in the CXCR5 gene, which plays a critical role in B cell navigation and lymphoid tissue development.
  • - Findings indicate that variations in the CXCR5 gene may contribute to the disease pathology in Egyptian patients with DLBCL, highlighting the potential implications for personalized treatment strategies in lymphoma.

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