Unusual late presentation of cryptococcal meningitis with simultaneous CMV antigenemia in a kidney transplant recipient.

Cryptococcosis is the third most common invasive fungal infection in solid-organ transplant (SOT) recipients after candidiasis and aspergillosis. These patients are at risk of disseminated cryptococcosis because of immuosuppressive therapy. The median time to disease onset after kidney transplantation is approximately 35 months and it rarely occurs more than 10 years after transplantation.

Food provision in Australian aged care homes does not meet protein needs of residents: A call for reform.

Aim: Malnutrition is common in older adults in aged care homes, partly due to inadequate protein intake. Menu planning guidelines are available however, adherence to guidelines is unknown. This study aimed to determine; (i) what are the average serving sizes of menu items provided and do they meet recommended portion sizes? (ii) does consumption from a 'typical' menu provide sufficient protein? and (iii) can substituting a 'typical' menu with high-protein options enable residents to achieve protein adequacy?

Methods: This study involved 572 residents (73% female; aged 86.

Topical oxygen therapy in the treatment of diabetic foot ulcers: a multicentre, open, randomised controlled clinical trial.

Objectives: Perfusion and blood oxygen levels are frequently insufficient in patients with hard-to-heal wounds due to poor circulation, vascular disruption and vasoconstriction, reducing the wound's capacity to heal. This study aimed to investigate the effect of topical oxygen on healing rates in patients with hard-to-heal diabetic foot ulcers (DFUs) (i.e.

A brief report on the clinical trial on neural mobilization exercise for joint pain in patients with rheumatoid arthritis.

Background: In rheumatoid arthritis (RA) synovitis, activation of synoviocytes and infiltration of adaptive immune cells leads to synovial hyperplasia and joint swelling. Under the elevated extra-neural pressure, free nerve endings release neuropeptides, calcitonin gene-related peptide, and substance P, thus promoting neurogenic inflammation.

Objective: This study aimed to assess the effect of therapeutic neural mobilization (NM) exercises targeting the nervous system on disease impact in RA patients.

Magnetic resonance imaging features of preserved vs divided and repaired piriformis during total hip arthroplasty: a randomized controlled trial.

The aim of this study was to compare the muscle grade and bulk of the divided and repaired piriformis tendon by the standard posterior approach with the preserved tendon by a piriformis-sparing (PS) approach, in total hip arthroplasty. Twenty-two patients were randomized to either approach. Patients received preoperative and 3 months and 2 years postoperative magnetic resonance imaging scans.

Mitigation of meconium-induced lung injury by surfactant and inhaled nitric oxide is associated with suppression of nuclear transcription factor kappa B.

Objective: To investigate whether the mechanism of a combined surfactant and inhaled nitric oxide (iNO) in improvement of oxygenation and mitigation of lung injury is associated with suppression of nuclear transcription factor kappa B (NF-kappaB) in the lung tissue of ventilated rabbits with meconium aspiration.

Methods: Adult rabbits (weight 2.0-3.

Varus/valgus alignment of the femoral component in total knee arthroplasty.

The position of the femoral component in 362 total knee replacements was assessed radiologically. A subgroup of 32 knees, 18 of which had perfect alignment and 14 with imperfect alignment underwent CT scout scans of the femur from which the mechanical axis of the femur could be measured. Radiologically 92% of all components were implanted within 3 degrees of the target value.

Fixed flexion deformity and flexion after knee arthroplasty. What happens in the first 12 months after surgery and can a poor outcome be predicted?

Fixed flexion deformity and flexion of 284 knee replacements were recorded pre-operatively at 6 weeks and 12 months after surgery. Eighteen knees (6.3%) achieved unsatisfactory movements at 12 months.