Publications by authors named "Lalu B Bramawangsa"
J Taibah Univ Med Sci
October 2024
Article Synopsis
- The study investigates the effectiveness and safety of hypertonic saline (HTS) compared to mannitol in reducing intracranial pressure (ICP) during brain tumor craniotomy in adults.
- A systematic review of eleven randomized controlled trials (RCTs) with 593 participants showed that HTS resulted in greater brain relaxation and lower urine output compared to mannitol, while also improving mean arterial pressure.
- While HTS was found to be superior in achieving brain relaxation, it did lead to higher plasma sodium levels, highlighting a trade-off in its usage during surgery.
