Publications by Laleh Khadembashi

Publications by authors named "Laleh Khadembashi"

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New 1H-pyrazole-4-carboxamides with antiplatelet activity.

Klaus Rehse Joscha Kotthaus Laleh Khadembashi

Arch Pharm (Weinheim)

January 2009

Nine title compounds were synthesized and investigated in the Born test for their antiplatelet activities against collagen, ADP, adrenaline, and platelet activating factor (PAF) as inducers of the aggregation. Using collagen three compounds with IC50 values below 100 microM were found (3b, 3e, 3i). Activities in nanomolar concentrations were observed against ADP (3b, IC50 = 9.

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