Therapeutics effects of bovine colostrum applications on gastrointestinal diseases: a systematic review.

Background: Evidence on the effects of bovine colostrum (BC) supplementation on gastrointestinal (GI) diseases is conflicting.

Objectives: This systematic review summarized the findings of clinical trials (CTs) on the effects of BC supplementation on GI diseases.

Methods: A systematic search was conducted in online databases, including PubMed, ISI Web of Science, and Scopus, until March 2021 and updated until December 2023.

Bovine Colostrum in Increased Intestinal Permeability in Healthy Athletes and Patients: A Meta-Analysis of Randomized Clinical Trials.

Background: Increasing intestinal permeability causes chronic inflammation, which is one of the etiological factors of many diseases that presently constitute global challenges.

Aims: Considering the importance of developing therapies to eliminate the increased intestinal permeability, in this systematic review and meta-analysis, we analyze the impact of bovine colostrum (BC) on the gut barrier and its permeability.

Methods: Online databases, including PubMed, ISI Web of Science, and Scopus, were searched to find pertinent articles up to March 2022.

Structure-based virtual screening, molecular docking, and molecular dynamics simulation approaches for identification of new potential inhibitors of class a β-lactamase enzymes.

Bacteria are smart organisms that create drug resistance by decreasing the effect of antibiotics in different ways, such as secretion of the β-lactamase enzymes. Finding the compounds that can act as the inhibitors of these enzymes is a great help in reducing drug resistance and treat all types of infections. In this study, using molecular docking and molecular dynamics simulation techniques, we introduced two Relebactam substructures as new inhibitors of class A β-lactamase enzymes.

Two-step optimization process for grass hydrolysate application as biodiesel feedstock with novel quality characteristics.

A major obstacle to biodiesel commercialization is supplying feedback which increases production costs. The potential of some oleaginous yeast for conversion of waste materials to biodiesel feedstock can overcome this problem. In this study, a potential oleaginous yeast strain was used for single-cell oil (SCO) production.

Species Variety, Antibiotic Susceptibility Patterns and Prevalence of Enterotoxin Genes in Staphylococci Isolated from Foodstuff in Central Iran.

Background: The presence and diversity of species and their enterotoxin-encoding genes in foodstuffs have not been comprehensively studied in some developing countries. This study aimed to assess the frequency of spp. and their related virulence factors in foodstuffs in Isfahan, Iran.

Species diversity and molecular analysis of Staphylococcus in confectioneries of a developing country, Iran.

Confectionery is one of the potential sources of contamination and transmission of gastrointestinal infections to humans. Staphylococcus species, and particularly the coagulase-positive ones, have the remarkable capability to produce high amounts of enterotoxin in food. In the present study, the frequency and diversity of Staphylococcus in confectioneries in Iran were assessed by using a combination of conventional and molecular methods.

Preconditioning by isoflurane as a volatile anesthetic in elective coronary artery bypass surgery.

Background: Some pharmacological preconditioning approaches are utilized as an effective adjunct to myocardial protection, particularly following cardiac procedures. The current study addressed the potential clinical implications and protective effects of isoflurane as an anesthetic most applicable on postoperative myocardial function measured by cardiac biomarkers.

Methods: 46 patients were included in the study.