Publications by authors named "Laleh Ghanei"
Hepatitis C virus infection is the major cause of liver cirrhosis. Antiviral treatment can achieve persistent viral clearance to prevent long-term complications of the disease. Despite the introduction of direct acting antivirals (DAAs) as effective therapy in recent years, the standard regimen consisting of interferon and ribavirin which are more accessible and inexpensive is still widely prescribed for the majority of worldwide hepatitis C patients in developing countries.
View Article and Find Full Text PDFBackground: The homeostasis model assessment of insulin resistance (HOMA-IR) is a useful model for application at large epidemiologic studies. The aim of this study was to determine the HOMA cut off values to identify insulin resistance (IR) and metabolic syndrome (MS) in Qazvin, central Iran.
Methods: Overall, 480 men and 502 women aged 20-72 yr attended in this cross sectional study from September 2010 to April 2011.
Article Synopsis
- This study investigates the link between vitamin D levels, dietary intake, and metabolic syndrome (MetS) among an Iranian population, highlighting the controversial nature of this relationship.
- The research involved comparing serum levels of 25(OH) D, calcium, and phosphorus between 122 patients with MetS and 128 controls, using various analytical methods to evaluate the data.
- Findings indicate that individuals with MetS had significantly lower levels of vitamin D and calcium intake, suggesting a potential association, but the exact mechanism remains unclear and needs further investigation.
Diabetes is a common metabolic disease in the world that has many adverse effects. Olibanum gum resin (from trees of the genus Boswellia) has traditionally been used in the treatment of various diseases such as diabetes. The aim of this study was the comparison of Olibanum gum resin effect with placebo on the treatment of type 2 diabetes.
View Article and Find Full Text PDFBackground: A low-glycemic index diet is effective in blood glucose control of diabetic subjects, reduces insulin requirement in women with gestation diabetes mellitus (GDM) and improves pregnancy outcomes when used from beginning of the second trimester. However there are limited reports to examine the effect of low glycemic load (LGL) diet and fiber on blood glucose control and insulin requirement of women with GDM. Therefore, the aim of this study was to examine the effect of low glycemic load diet with and without fiber on reducing the number of women with GDM requiring insulin.
View Article and Find Full Text PDFBackground: Very few studies have used community-based interventions for primary prevention of Type 2 diabetes, and the direct effect of such interventions on diabetes incidence is relatively unknown.
Purpose: This study aims to assess the effect of lifestyle modification on risk factors for noncommunicable diseases (NCDs) and the development of Type 2 diabetes at the community level.
Design: A cluster-controlled trial was conducted.