Publications by authors named "Laleewan Tajasuwan"
Defatted rice bran (DRB) is a by-product of rice bran derived after the oil extraction. DRB contains several bioactive compounds, including dietary fiber and phytochemicals. The supplementation with DRB manifests chemopreventive effects in terms of anti-chronic inflammation, anti-cell proliferation, and anti-tumorigenesis in the azoxymethane (AOM) and dextran sodium sulfate (DSS)-induced colitis-associated colorectal cancer (CRC) model in rats.
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- Defatted rice bran (DRB) is gaining popularity due to its rich nutritional profile and potential health benefits, including being a source of dietary fiber and phenolic compounds.
- A study demonstrated that DRB supplementation in rats with AOM/DSS-induced colorectal cancer (CRC) reduced cancer progression and symptoms, such as colonic shortening and disease activity.
- DRB also inhibited pro-inflammatory cytokines and cancer cell proliferation, suggesting it could serve as a natural dietary chemopreventive agent with significant implications for cancer prevention.