Publications by authors named "Lalan Kumar Arya"
Background: Children from coastal areas of South India develop granulomatous eye disease after swimming in their village ponds, the causative organism being trematode .
Aim: To understand the pathogenesis by analyzing the cellular profile, cytokines, and chemokines of aqueous fluid.
Methods: This was a prospective study over 1 year on pediatric patients with ocular granuloma caused by a Trematode Fluke sp.
Aim: To describe the characteristic clinical features and management of keratitis in the patients receiving miltefosine for post-kala-azar dermal leishmaniasis (PKDL).
Methods: The medical records of five patients with PKDL who presented with keratitis were reviewed retrospectively from April 2018 to December 2019. The evaluation included a thorough medical history including details on drugs used, particularly miltefosine.
Article Synopsis
- Trematodes are emerging parasites in tropical areas, specifically linked to ocular granulomas in children who bathe in South Indian water bodies.
- DNA from surgically removed granulomas and trematode larvae was analyzed using PCR techniques to identify the specific trematode responsible.
- The study confirmed that Procerovum varium, a type of trematode, is the cause of the ocular infections, highlighting the role of snail vectors as environmental risks.
Article Synopsis
- The study examined ocular symptoms in patients with West Nile virus (WNV) using advanced diagnostic methods over a two-year period.
- Out of 52 patients, 71% tested positive for WNV, suffering from various retinal inflammations and complications, with many showing decreased vision.
- Diagnostic techniques used included various forms of imaging and laboratory tests, with some patients achieving improved visual acuity by the end of the study.
Duane retraction syndrome (DRS) is a congenital eye movement disorder characterized most typically by partial or complete failure of abduction and narrowing of palpebral fissure with globe retraction on adduction. Recently mutations of the SALL4 gene on chromosome 20 have been linked to DRS associated with radial forearm malformations (Okihiro syndrome). In this prospective, non-interventional study we screened for SALL4 mutations in 72 patients clinically diagnosed as having isolated DRS or DRS associated syndromes.
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