Functional polymorphisms of the receptor for the advanced glycation end product promoter gene in inflammatory bowel disease: a case-control study.

The receptor for the advanced glycation end products (RAGE) is a multiligand transmembrane receptor involved in chronic inflammation whose specific polymorphisms of the promoter gene were found to increase its transcriptional activity. We investigated the association of both allelic and genotypic -374T/A and -429T/C polymorphisms with inflammatory bowel disease. The STREGA guidelines were applied for planning and reporting.

Effect of equal daily doses achieved by different power densities of low-level laser therapy at 635 nm on open skin wound healing in normal and diabetic rats.

Background And Objective: Despite the fact that the molecular mechanism of low-level laser therapy (LLLT) is not yet known, the exploitation of phototherapy in clinical medicine and surgery is of great interest. The present study investigates the effects of LLLT on open skin wound healing in normal and diabetic rats.

Materials And Methods: Four round full-thickness skin wounds on dorsum were performed in male adult nondiabetic (n = 24) and diabetic (n = 24) Sprague-Dawley rats.

Trehalase as a possible marker of intestinal ischemia--reperfusion injury.

Background: Different pathological affections of the small intestine cause corresponding morphological and functional changes. The present study was aimed to assess intestinal trehalase activities during ischemia and following reperfusion, correlate them with the pathological changes and determine whether trehalase could be used as a biochemical marker of the intestinal ischemia, ischemia - reperfusion injury.

Material And Methods: Wistar rats, randomly divided into 5 experimental groups (IR) (each n=15), were subjected to one hour mesenteric ischemia followed by 0, 1, 4, 12 and 24 hours of reperfusion.

[Acute multiple organ failure after endoscopic polypectomy].

Background: Serious intraabdominal infections belong among life treating diseases. They are based on spreading infections from focal sources of inflammation in abdomen or damaged intestinal wall.

Methods And Results: Treatment strategies are surgical intervention, antimicrobial therapy, distributional shock treatment and accurate nutritional support (1).

[Heterotopic pancreas in the stomach wall -- a rare histological diagnosis of submucous lesson -- casuistic report].

Heterotopic pancreas (HP) is defraed as abnormally localized pancreatic tissue without any anatomical and vascular connection with pancreas. Incidence of HP is 0.2-0.

Obturator artery injury after hip fracture surgery.

We present the case of a 55-year-old woman who sustained a left femoral neck fracture which was managed by insertion of a dynamic hip screw. Six hours after surgery, distension appeared in the left lower quadrant of her abdomen associated with a decline in haemoglobin concentration and clinical signs of ongoing bleeding. Computed tomography showed a left retroperitoneal mass without concomitant extravasation of contrast material.

Low-level laser therapy for protection against skeletal muscle damage after ischemia-reperfusion injury in rat hindlimbs.

Background And Objective: Despite numerous hypotheses regarding the action of laser light, the use of low-level laser therapy (LLLT) in ischemic reperfusion (I/R) injury is still being verified. The present study investigates the effects of low-level laser irradiation (LLLI) on I/R injury of the musculus gracilis in rats.

Materials And Methods: I/R injury of the musculus gracilis flap was induced in male adult Sprague-Dawley rats (n = 84).

[Have changes in the management of treatment of the patients with acute pancreatitis brought the expected result?].

Background: Mortality from severe acute pancreatitis (AP) has remarkably decreased (10-20%) during the last decades. However, many questions on the treatment of this disease remained opened. To extend the most recent professional literature which discuses the abovementioned problem, experience from the treatment of patients at the department where the authors work is presented.

[A rare complication following anastomosis suturing using a biofragmentable Valtrac anastomosis ring--a case review and literature overview].

The use of Valtrac Ring since 1985 has brought about the ability of easier anastomosis suturing and shortening of the operative treatment. As other methods, also Valtrac ring has its disadvantages. Authors present a case report of a complication previously not described in the literature.

[Uncommon rectal adenocarcinoma metastases].

Rectal cancer treatment has become multimodal as a result of significant advances in imaging diagnostic, in surgery technique of re section and in neo and adjuvant therapy. The aim of the case report was to present a successfully treated adenocarcinoma recti and adenocarcinoma of hepatal flexurae with recidivistic metastasis and an extremely rare intergrowth of the metastasis into venous system. A 61 year old patient underwent low resection of recti according to Dixon because of well differentiated adenocarcinoma with classification T3N0M0.

[Pseudodiverticulitis coeci--the atypical etiology of right iliac fossa pain--a case report].

The aim of our paper is to show on the diagnosis of coecal diverticul as infrequent reason of right iliac fossa pain. We present the case report of 43-years old woman, which underwent appendectomy some years sooner, and was accepted into the hospital because of 48-hours taking right iliac fossa pain. Local peritoneal irritation was present.

[Arteriovenous malformation in small intestine as atypical etiology of lower gastro-intestinal bleeding--a case report].

Lower gastrointestinal tract bleeding (LGIB) is the acute abdomen, defined as gastrointestinal tract bleeding under the ligament of Treitz. We present the case report of patient iteratively hospitalized because of repeated LGIB. There were performed gastrofibroscopy, colonoscopy and capsule endoscopy, without the bleeding localization.

[Mesenteric ischemia--late diagnosis or managed disease?].

Aim: Diagnosis and therapy of mesenteric ischaemia as the cause of an acute abdomen is a serious problem because of its 60-80% mortality. The study presents experience with diagnosis and therapy of this disease and it compares its results with those in the literature.

Material And Results: Throughout the years 2000-2009, there were 39 patients surgically treated with mesenteric ischaemia (17 men, 21 women, the average age 73 I 9.

[Diverticulitis appendicis vermiformis--a case review and literature overview].

Background: Diverticulosis and diverticulitis of appendix vermiformis is a rare diagnosis with incidency of 0.004-2%. Because of intermittent pain and atypical problems patients with diverticulitis are surgically intervened later as patients with simplex appendicitis.

[Giant solitary fibrous tumor of the pleura--case report].

Solitary fibrous tumors of the pleura are rare malignant pathological findings, accounting for only 5% of all pleural neoplasms. Clinical manifestations are very unspecific and over 50% of the cases are asymptomatic. The commonest clinical symptoms include cough, pains, dyspnoea, fever and weight loss.

[Appendix protrusion from perforation of uterus--the rare complication during abortion].

Aim: Point to an extremly rare complication of a curettage during abortion and follow up surgical treatment of this complicated state.

Case: In the case of 32 years old woman, multipara, was perforated cervix uteri during the abortion curettage and fat tissue of mesentery was aspirated into canulla. Apendix vermiformis was aspirated into cannula with its protrusion through the neck of the womb during repeated revision.

[Low molecular weight heparins and their non-antithrombotic effects on wound healing].

Heparin and low molecular weight heparins (LMWHs) are commonly indicated drugs for surgery and non-surgery patients because of their effectiveness and safety in prevention and therapy of deep vein thrombosis. While the effect of LMWHs on coagulation cascade is commonly known, some other effects of these drugs are unknown. Many papers present anti-inflammatory effects of LMWHs.

[Appendicitis in pregnancy].

Unlabelled: THE AIM OF THE STUDY was to highlight the problems related to acute appendicitis in pregnancy. We present our own experiences with the diagnostics and therapy of this surgical complication during gravidity. Nausea, vomiting and pain in lower right abdomen as symptoms of appendicitis are often confused with the I.

[Re-expansion pulmonary edema as a complication of a spontaneous pneumothorax drainage--a case review].

Reexpansion pulmonary edema is an iatrogenic complication occurring after reinflation of the collapsed lung of a patient with pneumothorax or fluidothorax. The following risk factors have been associated with reexpansion pulmonary edema: younger age, longer duration of a lung collapse, its large extend and a quick lung reexpansion. We report a case of 26-years-old man.

[Chronic wound as a precancerosis (Ulcus marjolini--Marjolin's ulcer)--a case review].

Marjolin's ulcer is defined as a tumor arising from a chronic wound, scar or chronic inflammation. Commonly, it is histologically diagnosed as a squamous cell carcinoma or a basocellular carcinoma. Its management includes its excisioning including a sufficient circumferential rim and histological examination of the sentinel lymphnode.

[Parenteral nutrition before surgery in patients with upper gastrointestinal tract resection].

Background: The aim of this retrospective analysis was the evaluation of the effect of parenteral nutrition before surgery in malnourished patients on the reduction of risks during postoperative period after upper gastrointestinal tract resection. 57 patients with the diagnosis of oesophageal or stomach carcinoma were included into the selected group. Patients were divided into three groups: I.

[Venous ulcer--present view on aetiology, diagnostics and therapy].

The common aetiology of chronic wounds is chronic venous insufficiency. The prevalence of chronic venous insufficiency ranges from 5 to 8% and the prevalence of venous ulcers is about 1%. Venous ulcer is caused by induction of chronic inflammation.

[Spontaneous rupture of ductus choledochus in acute pancreatitis--a case report].

Spontaneous perforation of biliary tree is a rare disease. There are only a few case- reports published in the literature. Due to little success in the preoperative diagnosis, surgical treatment is delayed, which in a high percentage results into fatal complications.

[Biliary ileus--a rare complication of cholecystolithiasis].

The diagnosis of ileus caused by biliary stones occurs very rarely, with the range of 2 % worldwide. This complication of cholecystolithiasis caused by the stone fistulation into gastrointestinal tract and its subsequent obstruction occurs mostly in elderly and has a high mortality rate. During the course of ten years (1996-2006) in the 2nd surgical clinic FNLP in Kosice, 1640 cholecystectomies and 255 operations, due to the obstruction ileus, were performed.