Concurrent tubercular involvement of two or more non-contiguous organs is termed disseminated tuberculosis (TB) and is rare in immunocompetent patients. We describe the case of a young immunocompetent woman with disseminated TB who presented with primary complaints of amenorrhea and dysuria. Abdominal ultrasound showed a uterine cervical mass, which on histopathological evaluation revealed epithelioid granulomata with Langhans giant cells and acid-fast bacilli (AFB).
View Article and Find Full Text PDFWe present the case of a 59-year-old man from South India who presented with shortness of breath, abdominal distention, and decreased appetite. Initial laboratory investigations and imaging, including radiolabeled somatostatin positron emission tomography-computed tomography, were suggestive of neuroendocrine tumor (NET). However, following extensive workup and multiple biopsies over several weeks, the diagnosis was revised to extrapulmonary tuberculosis (EPTB).
View Article and Find Full Text PDFMetronidazole, a commonly used antiprotozoal agent, has been linked to neurotoxicity in a few individuals. We present the case of a 61-year-old gentleman diagnosed with a liver abscess, who received a total dose of 64 g of metronidazole over a four-week duration. He subsequently developed slurred speech, numbness, and tingling sensation in both feet.
View Article and Find Full Text PDFBackground: Nonsurgical periodontal therapy results in the formation of a smear layer which inhibits tissue regeneration. Root biomodification (RB) using various agents has been tried for the enhancement of new attachment formation. However, no substantial therapeutic advantages of currently available root conditioning agents have been reported emphasizing the need for additional biologically acceptable agents.
View Article and Find Full Text PDFExpression of concern for 'High performance flexible supercapacitors based on secondary doped PEDOT-PSS-graphene nanocomposite films for large area solid state devices' by Syed Khasim , , 2020, , 10526-10539, https://doi.org/10.1039/D0RA01116A.
View Article and Find Full Text PDFBackground: Aedes-borne disease risk is associated with contemporary urbanization practices where city developing structures function as a catalyst for creating mosquito breeding habitats. We lack better understanding on how the links between landscape ecology and urban geography contribute to the prevalence and abundance of mosquito and pathogen spread.
Methods: An outdoor longitudinal study in Bengaluru (Karnataka, India) was conducted between February 2021 and June 2022 to examine the effects of macrohabitat types on the diversity and distribution of larval habitats, mosquito species composition, and body size to quantify the risk of dengue outbreak in the landscape context.
Background: Oral cancers are often detected at late stages, and patients usually had a 50% chance of a 5-year survival rate. Oral cancer usually has an early precancerous stage before its actual malignant transformation. Although there are various approaches to diagnose the early stages of cancer, there is one less explored, cost-effective, and simple technique known as the crystallization test.
View Article and Find Full Text PDFUnlabelled: Bacterial panicle blight (BPB) caused by (BG) has become significantly more prevalent in the rice-growing regions of North India. Based on virulence screening and in vitro quantification of toxoflavin, the BG strains were classified as hyper- (BG1 and BG3), moderate- (BG2, BG4, BG6, BG8, and BG9), and hypo- (BG5, BG7, and BG10) virulent. Plant inoculation assays with cell-free culture filtrate revealed strains with higher toxoflavin-producing ability had higher virulence.
View Article and Find Full Text PDFUnlabelled: pv. (Xoo) is a pathogen of concern for rice growers as it limits the production potential of rice varieties worldwide. Due to their high genomic plasticity, the pathogen continues to evolve, nullifying the deployed resistance mechanisms.
View Article and Find Full Text PDFIn this research, we demonstrate a Deep Convolutional Neural Network-based classification model for the detection of monkeypox. Monkeypox can be difficult to diagnose clinically in its early stages since it resembles both chickenpox and measles in symptoms. The early diagnosis of monkeypox helps doctors cure it more quickly.
View Article and Find Full Text PDFJ Oral Maxillofac Pathol
December 2022
Background: The aerosols generated during dental treatments contain bacteria and other microorganisms that penetrate the body through the respiratory system of dental surgeons and cause infectious diseases. Several studies have been done to reduce these hazards. The aim of the present study is to evaluate the effects of the plant extract essential oil (EO) vapors of Neem, Clove, Cinnamon bark, Thyme, Lemon Grass, and on the bacterial count in bioaerosols near dental units.
View Article and Find Full Text PDFIntroduction Unless specifically asked, many patients may be hesitant to discuss their experiences. Some people might not recall what happened right after surgery, but they might remember it 1-2 weeks later. We undertook the current study to estimate the incidence of awareness among patients under general anesthesia (GA).
View Article and Find Full Text PDFObjectives: Root coverage (RC) is an integral part in management of gingival recessions. Unlike isolated recessions, treating multiple recessions is the most challenging scenario especially in smokers who have reported reduced RC in terms of quantity and stability. Modified coronally advanced tunnel (MCAT) technique due to its improved vascularity along with use of porcine-derived collagen matrix (PDCM) (Mucograft™) with its bilayered dense collagen matrix may be a predictable alternative to conventional gold standard subepithelial connective tissue graft (SCTG).
View Article and Find Full Text PDFMinor salivary gland neoplasms constitute up to approximately 25% of all salivary gland tumors. The incidence of malignancy of these tumors is slightly greater than half. Basal cell adenocarcinoma (BCAC) is a rare salivary gland malignancy that occurs most commonly in the parotid gland.
View Article and Find Full Text PDFAn expeditious method for the synthesis of monosaccharides and disaccharides possessing 3-oxo-glycal units is revealed. Several monosaccharides and disaccharide-derived glycals are converted to the corresponding hexenuloses in three steps involving halo-alkoxylation, dehydrohalogenation, and ketalyzation reactions. A number of 3-oxo-glycals are synthesized to show the methodology's importance and generality.
View Article and Find Full Text PDFObjective: Patients experiencing an intracranial hemorrhage (ICH) on oral anticoagulants often require rapid reversal. This study evaluated patients taking factor Xa inhibitors or warfarin that received reversal with 4-factor prothrombin complex concentrate (4F-PCC) for an ICH. The objective of the study was to determine if the efficacy of 4F-PCC for the reversal of factor Xa inhibitors is noninferior to its use in warfarin reversal in patients with ICH.
View Article and Find Full Text PDFBackground: The objective of the study was to identify the factors that alter the length of hospital stay of COVID-19 patients so we have an estimate of the duration of hospitalization of patients. To achieve this, we used a time to event analysis to arrive at factors that could alter the length of hospital stay, aiding in planning additional beds for any future rise in cases.
Methods: Information about COVID-19 patients was collected between June and August 2020.
The use of prostate MRI for prostate cancer evaluation continues to rise and ensuring minimum quality standards across practices will enable optimal diagnostic accuracy and thus, patient care. The American College of Radiology has been working on quality standards to meet Prostate MRI Designated Center, which is expected to launch in late 2020. We discuss the background of the American College of Radiology Prostate MRI working group's effort and summarize the criteria for Prostate MRI Designation.
View Article and Find Full Text PDFProlidase enzyme, which catalyzes the final step in collagen metabolism can influence the cognitive functions through changes in extracellular matrix (ECM) resulting in altered synaptic connectivity in Alzheimer's disease (AD). In this study, it was found that the prolidase activity was significantly higher (p = 0.0016) in AD subjects (5.
View Article and Find Full Text PDFIn this work, we propose the development of high performance and flexible supercapacitors using reduced graphene oxide (rGO) incorporated poly(3,4 ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT-PSS) nanocomposites by secondary doping. The structural and morphological features of the composite film were analyzed in detail using SEM, AFM, FTIR, XPS and TGA. Secondary doping of ethylene glycol (EG) assisted by rGO incorporation significantly enhances the room temperature conductivity of PEDOT-PSS films from 3 S cm to nearly 1225 S cm for a 10 wt% composite.
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