Publications by authors named "Lais S de Azevedo"
Article Synopsis
- The study focuses on analyzing Brazilian rotavirus strains G12P[6] and G12P[9] from 2011 to 2020 to understand genetic relationships between human and animal-origin strains using RT-PCR and sequencing techniques.
- Findings indicate that G12P[6] strains show distinct genetic clustering and are associated with African ancestry and American strains, while G12P[9] strains exhibit unique lineages found only in Brazil, suggesting local evolution.
- The results highlight a common origin for South American G12P[9] strains, supporting the idea of their introduction from Asia, with no recent reassortments from globally circulating strains.
This study aimed to investigate the frequency and genotypic diversity of human bocavirus (HBoV) in historical fecal samples collected before 2005 in Brazil and understand its natural history in patients with diarrhea. Between 1998 and 2005, 3347 samples were tested for HBoV by RT-PCR, with a detection rate of 5.8% (195/3347).
View Article and Find Full Text PDFRotavirus (RVA) G8 is frequently detected in animals, but only occasionally in humans. G8 strains, however, are frequently documented in nations in Africa. Recently, an increase in G8 detection was observed outside Africa.
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- This study focused on the epidemiology of human astroviruses in children under 5 in Tocantins State, Brazil, from 2010 to 2016.
- Out of 232 stool samples, 16 (6.9%) tested positive for HAstV using both Next-Generation Sequencing (NGS) and conventional RT-PCR methods.
- The findings highlighted the genotypic diversity of HAstV, with lineages identified as HAstV-1a (9 cases), HAstV-4c (3 cases), and HAstV-5c (4 cases).
During 2006-2011, 5035 fecal samples were tested by PCR for human adenovirus (HAdV) and sequenced. HAdV was detected in 198 cases (3.9%), with the highest rate in children ≤ 5 years.
View Article and Find Full Text PDFEpizootics due to Yellow Fever Virus in São Paulo State, Brazil: viral dissemination to new areas (2016-2017).
Sci Rep
April 2019
Beginning in late 2016 Brazil faced the worst outbreak of Yellow Fever in recent decades, mainly located in southeastern rural regions of the country. In the present study we characterize the Yellow Fever Virus (YFV) associated with this outbreak in São Paulo State, Brazil. Blood or tissues collected from 430 dead monkeys and 1030 pools containing a total of 5,518 mosquitoes were tested for YFV by quantitative RT-PCR, immunohistochemistry (IHC) and indirect immunofluorescence.
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