Publications by authors named "Laio Magno"
Background: Consistent monitoring of PrEP adherence with accurate measurement tools at point-of-care could greatly contribute to reaching adolescents with poor adherence. We aimed to assess the performance of indirect adherence measures to oral PrEP among adolescent men who have sex with men (AMSM) and adolescent transgender women (ATGW).
Methods: PrEP15-19 is a prospective, multicenter, PrEP demonstration cohort study that includes AMSM and ATGW aged 15-19 in three Brazilian cities.
Background: Programs offering financial support have been established to mitigate the economic fallout and vulnerabilities arising from the COVID-19 pandemic. Moreover, financial incentives were introduced to promote compliance with social isolation measures, thereby preventing SARS-CoV-2 infections and transmission. However, few low- and middle-income countries have implemented financial aid to alleviate the socio-economic impact of the COVID-19 pandemic.
View Article and Find Full Text PDFArticle Synopsis
- The study aims to compare the social and HIV vulnerability of adolescents from sexual minorities who started pre-exposure prophylaxis (PrEP) at community-based organizations (COs) versus a traditional health service in São Paulo.
- It found that adolescents at COs had quicker access to PrEP and generally faced lower housing development indicators, indicating higher social vulnerability.
- Despite being more socially vulnerable, adolescents from COs did not exhibit higher-risk sexual behaviors compared to those using traditional services, suggesting that COs improve access without increasing risk.
Article Synopsis
- - The article explores how PrEP and the concept of undetectable viral load creating a framework (UVL=U) have changed the dating and sexual experiences of young gay men living with HIV in Brazil.
- - Interviews with nine young people (ages 18-29) reveal that those newly diagnosed are more worried about HIV transmission and stigma, while those who have lived with HIV longer feel more at ease with these new biomedical advances.
- - The findings highlight the need for inclusive public health policies that go beyond just medical solutions, addressing stigma, enhancing knowledge about HIV prevention, and respecting individuals' choices in managing their sexual health.
Article Synopsis
- This study investigates viral hepatitis prevalence among young men who have sex with men (MSM) and transgender women (TGW) in three Brazilian cities, focusing on those aged 15-19.
- The research collected data through social behavioral questionnaires and blood tests to check for hepatitis A, B, and C antibodies and active infections.
- Results showed 17.7% had immunity to hepatitis A, while hepatitis B and C prevalence was lower at 2.8% and 0.2%, respectively, indicating a need for improved vaccination and treatment strategies in these populations.
Objective: To identify recent HIV-1 infection and estimate HIV incidence among adolescent men who have sex with men (AMSM) and transgender women (ATGW) in Brazil.
Methods: From January to December 2020, a cross-sectional analysis was conducted with baseline data from the PrEP1519 study, an HIV pre-exposure prophylaxis (PrEP) demonstration cohort in Brazil among sexually active AMSM/ATGW aged 15-19. For enrollment, participants were screened with a fourth-generation HIV rapid test.
Article Synopsis
- The study examines factors influencing HIV self-testing (HIVST) uptake among adolescent men who have sex with men (AMSM) and adolescent transgender women (ATGW) before and during the COVID-19 pandemic.
- Findings show a decrease in HIVST uptake from 44.9% pre-pandemic to 35.5% during the pandemic, with specific sexual behaviors affecting these rates differently in each period.
- The research suggests that HIV programs should adjust their service delivery models to better address the changing needs of adolescents and young people to improve testing rates and reach individuals who are undiagnosed.
Our objective was to compare HIV prevalence between two national surveys among men who have sex with men in Brazil in 2009 and 2016. HIV prevalence was estimated stratifying by age and socioeconomic status. HIV prevalence increased from 11.
View Article and Find Full Text PDFObjective: The objective of the present study is to describe the sociodemographic and behavioral characteristics of a group of transgender women and travestis (TGW) with a history of incarceration and the institutional and social context of this experience in Brazil.
Methods: The analyzed data were derived from the TransOdara Study, a cross-sectional study conducted in five Brazilian capitals from December 2019 to July 2021. Participants were recruited using the Respondent-Driven Sampling (RDS) technique, in which, after an initial formative and exploratory stage, the first participants were identified; in turn, these participants recruited up to six other transgender women and travestis for the research.
Objective: To identify groups of transgender women and travestis (TGW) with specific patterns of gender-based discrimination (GBD) and analyze the factors associated with GBD.
Methods: A cross-sectional study was conducted with TGW recruited through respondent-driven sampling in five Brazilian cities (2019-2021). Latent class analysis was used to characterize GBD (low, medium, and high) using 14 observable variables.
Objective: To investigate the prior testing for HIV, syphilis, hepatitis B (HBV), and hepatitis C (HCV) among transgender women and travestis (TGW) in five Brazilian cities and identify factors associated with each of these previous tests.
Methods: This is a cross-sectional study with the recruitment of TGW through respondent-driven sampling (TransOdara Study). The investigated outcome variable was prior testing for HIV, syphilis, HBV, and HCV in the last 12 months.
Article Synopsis
- - The study aimed to determine the prevalence and contributing factors of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections in transgender women and travestis across five Brazilian cities from 2019 to 2021.
- - A total of 1,297 participants were analyzed, revealing CT prevalence at 11.5%, NG at 13.3%, and coinfection at 3.6%, with certain factors like sex work and injectable drug use significantly linked to higher infection rates.
- - The findings highlight that transgender individuals, especially younger ones involved in sex work and illicit drug use, experience greater prevalence of sexually transmitted infections compared to the general population.
Objective: To estimate the prevalence and factors associated with hepatitis A, B, and C in transgender women and travestis's networks, in 5 regions of Brazil.
Methods: This cross-sectional study includedtransgender women and travestis in five Brazilian capitals (Campo Grande, Manaus, Porto Alegre, Salvador, and São Paulo), between December/2019 and July/2021. All samples were subjected to detection of serological markers of hepatitis virus A (HAV), B (HBV), and C (HCV) infections through rapid tests and chemiluminescent microparticle immunoassays.
Objective: The aim of this study was to investigate the prevalence of human immunodeficiency virus (HIV) infection among transgender women and travestis and to analyze factors associated with HIV infection in Brazil.
Methods: TransOdara was a cross-sectional study on sexually transmitted infections among transgender women and travestis in five Brazilian cities between 2019 and 2021. Self-identified transgender women and travestis aged ≥18 years were recruited using respondent-driven sampling, completed an interviewer-led questionnaire, and provided samples to detect HIV.
Objective: Sexually transmitted infections (STIs) disproportionately affect transgender women and travestis (TGW), who often lack access to healthcare due to stigma and discrimination. We describe the approach and methodology of a study investigating the prevalence of syphilis, HIV, hepatitis A, B, and C, Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), and human papillomavirus (HPV) among TGW, as well as their knowledge and perceptions regarding syphilis, to better inform policies to curb STIs among this vulnerable population.
Methods: TransOdara was a multicentric, cross-sectional study conducted among TGW in five capital cities from major Brazilian regions between December 2019 and July 2021.
Objective: To analyze HIV Post-Exposure Prophylaxis (PEP) prescription and return for follow-up appointments.
Methods: This was a descriptive cross-sectional study using data on people who sought PEP in emergency care units (UPAs) and specialized medical services in Salvador, BA, Brazil, between January-December/2018.
Results: Of the 1,525 people who sought PEP at UPAs, 1,273 (83.
Stigmatisation processes constitute key barriers to effectively addressing the HIV pandemic. In this article, we provide a critical overview of this field's current state of the art, highlighting some key emerging issues that merit greater research attention in the future to ensure that contemporary research on stigmatisation and resistance processes continues to engage with changing social and political circumstances. We look at how resistance to stigma has developed in the context of HIV and highlight some of the most important programmatic strategies that have emerged over the history of the pandemic.
View Article and Find Full Text PDFBackground: Primary Health Care (PHC) is essential for effective, efficient, and more equitable health systems for all people, including those living with HIV/AIDS. This study evaluated the impact of the exposure to one of the largest community-based PHC programs in the world, the Brazilian Family Health Strategy (FHS), on AIDS incidence and mortality.
Methods And Findings: A retrospective cohort study carried out in Brazil from January 1, 2007 to December 31, 2015.
Article Synopsis
- This study assessed the diagnostic performance of two antigen-detecting rapid tests for SARS-CoV-2 in resource-limited settings in Salvador, Brazil, focusing on individuals with COVID-19 symptoms or exposure.
- The Abbott and WAMA tests both exhibited high specificity (100%) but lower sensitivity rates (52.7% and 53.4%, respectively), particularly when compared to the gold standard RT-PCR.
- While both tests are effective for quickly identifying potential COVID-19 cases, negative results require careful clinical evaluation, especially for patients with lower viral loads indicated by Cycle Threshold values below 24.
"It was unusual but amazing": demand creation for PrEP among adolescents' men who have sex with men (MSM) and transgender women (TGW) in Brazil.
Cad Saude Publica
May 2024
This study aimed to analyze the challenges in demand creation for participation in an HIV pre-exposure prophylaxis (PrEP) project in two Brazilian capitals. This qualitative study was conducted with men who have sex with men and transgender women aged 15 to 19 years who lived in two Brazilian state capitals. For this analysis, 27 semi-structured interviews carried out from 2019 to 2020 were evaluated by reflexive thematic content analysis.
View Article and Find Full Text PDFThe relationships between race, education, wealth, their intersections and AIDS morbidity/mortality were analyzed in retrospective cohort of 28.3 million individuals followed for 9 years (2007-2015). Together with several sensitivity analyses, a wide range of interactions on additive and multiplicative scales were estimated.
View Article and Find Full Text PDFThis study aims to estimate the COVID-19 vaccine acceptance and hesitancy among people living with HIV (PLWHA). A search for observational studies was conducted in five databases and preprinted literature. Summary estimates were pooled using a random effects model and meta-regression.
View Article and Find Full Text PDFAcceptability and Usability of Self-Sampling for the Detection of Sexually Transmitted Infections Among Transgender Women: The TransOdara Multicentric Study in Brazil.
Sex Transm Dis
April 2024
Background: The effective testing of sexually transmitted infections (STIs) requires sampling from potential infection sites. This study aimed to assess the choice, satisfaction, and performance of self-collected samples (SCS) from potential infection sites for STI testing among transgender women in Brazil.
Methods: TransOdara was a multicentric, cross-sectional STI prevalence study conducted in 5 Brazilian cities.