Publications by authors named "Laila Latifi"
Genome manipulation methods in C. elegans require microinjecting DNA or ribonucleoprotein complexes into the microscopic core of the gonadal syncytium. These microinjections are technically demanding and represent a key bottleneck for all genome engineering and transgenic approaches in C.
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- Genome manipulation methods require precise microinjections of DNA or ribonucleoprotein complexes into a specific part of the organism, but these techniques are complex and slow.
- A new method utilizing a simple paintbrush for handling worms during microinjections has nearly tripled the injection rates compared to traditional methods.
- This paintbrush technique not only boosts injection efficiency and survival rates for experienced researchers but also makes the process easier for novices, potentially accelerating strain development in the research community.