Treatment of an accident of imidacloprid poisoning.

Accidental oral imidacloprid poisoning occurred in a family in Shandong, China, in May 2023. This study aimed to analyze the clinical characteristics of this imidacloprid poisoning event and investigated the detection of toxicants. Clinical data of four patients with oral imidacloprid poisoning were collected and retrospectively analyzed.

Case report: Occupational poisoning incident from a leak of chloroacetyl chloride in Jinan, Shandong, China.

Chloroacetyl chloride is a potent acylation agent that decomposes violently in water to produce chloroacetic acid and irritant hydrogen chloride. It and its decomposition products are corrosive to the eyes, skin, and respiratory system and can cause multiple organ failure. Herein, we report cases of poisoning by chloroacetyl chloride and its decomposition products in the skin and respiratory system.

Unique MicroRNA signatures associated with early coronary atherosclerotic plaques.

The pathophysiology of coronary atherosclerotic plaques is a complex process. Early detection of coronary atherosclerotic plaques is critical in the prevention, prognostic and therapeutic intervention of cardiovascular disease. MicroRNAs (miRNAs), endogenous short non-coding RNAs, have been reported to play an important role in cardiovascular diseases and are also used as disease markers.

Panel-reactive antibody levels and renal transplantation rates in sensitized patients after desensitization and human leucocyte antigen amino acid residue matching.

Objective: To determine whether a new desensitization protocol (mycophenolate mofetil [MMF], plasmapheresis and antithymocyte globulin [ATG], complemented with human leucocyte antigen [HLA] amino acid residue matching) could reduce panel-reactive antibody (PRA) levels in sensitized patients, to facilitate successful renal transplantation.

Methods: Patients awaiting transplantation with PRA levels >10% received treatment with MMF; those with PRA levels >30% were also treated with plasmapheresis. Patients whose PRA level was <20% after desensitization were eligible for transplantation.

Clinical significance of MMP-7 and PTEN expression in colorectal cancer.

Background/aims: The aim of this study was to investigate the expression of MMP-7 and PTEN protein in colorectal cancer and explore its correlation with clinicopathological parameters.

Methodology: In colorectal cancer tissue samples (n=48) and normal rectal tissue samples (n=23), the expression of MMP-7 and PTEN was detected by immunohistochemistry. Using medical records, the relationship of MMP-7 and PTEN expression with clinicopathological parameters was analyzed.