Publications by authors named "Laiba Ahmed"
Article Synopsis
- Heparan sulfate (HS) is important for cellular signaling, with its function influenced by the enzyme HS6ST2, particularly in the brain.
- Research on Hs6st2 knockout mice revealed that the absence of this enzyme leads to decreased HS 6-O-sulfation and increases body weight along with metabolic dysfunctions.
- Behavioral assessments showed memory deficits in these mice, correlating with transcriptomic changes in the hippocampus, highlighting the significance of Hs6st2 in memory and its potential link to brain disorders.
