Publications by authors named "Laia Pons"

Article Synopsis
  • The study explores natural plant ingredients, bakuchiol (BAK) and Vigna aconitifolia extract (VAE), as enhancements to the retinoid retinal (RAL) for anti-aging benefits, with fewer side effects.
  • Methods included gene expression profiling, assessing skin irritation, and a clinical study to test a cosmetic formulation combining these ingredients with others like niacinamide and melatonin.
  • Results showed that the tri-retinoid complex (3RC) significantly improved skin characteristics, such as firmness and elasticity, while reducing wrinkles, with 100% of participants seeing a decrease in crow's feet after 28 days of use.
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Olive mill wastes represent an important environmental problem. Their high phenol, lipid, and organic acid concentrations turn them into phytotoxic materials. Specifically, wet olive pomace (WOP) is the waste generated in the two-phase continuous extraction process.

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Background: In endothelial dysfunction, vascular cell adhesion molecule-1 (VCAM-1), E-selectin and intercellular adhesion molecule-1 (ICAM-1) expression (collectively termed cell adhesion molecules; CAMs) increase at sites of atherosclerosis and are stimulated by proinflammatory cytokines such as tumor necrosis factor-α (TNF-α).

Methods: We evaluated the effect of alpha-tocopherol (AT; 10-150 µM) and BAY 11-7082 (BAY; 0.1 or 1 µM) on CAMs mRNA expression as well as their protein in soluble release form (sCAMs) in human aortic endothelial cells (HAECs) activated by TNF-α (1 or 10 ng/ml).

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