Publications by authors named "Laia Albiach"
Purpose: Assess the impact of viral load estimated by cycle threshold (Ct) of reverse transcription real time-polymerase chain reaction (rRT-PCR) and the days from symptoms onset on mortality in hospitalized patients with COVID19.
Methods: Retrospective observational study of 782 patients with a positive rRT-PCR from a nasopharyngeal swab was performed within the first 24 h from admission. Demographic data, clinical manifestations and laboratory parameters were collected.
Introduction: Increased mortality has been reported in the Latin American population. The objective is to compare the clinical characteristics and outcome of Latin American and Spanish populations in a cohort of patients hospitalized with COVID-19 during the first year of the pandemic.
Methods: We retrospectively analysed all the Latin American patients (born in South or Central America) hospitalized in our centre from February 2020 to February 2021 and compared them with an age- and gender-matched group of Spanish subjects.
Dexamethasone and tocilizumab have been associated with reduction in mortality, however, the beneficial effect is not for all patients and the impact on viral replication is not well defined. We hypostatized that C-reactive protein (CRP) could help in the identification of patients requiring anti-inflammatory therapy. Patients admitted for > 48 h in our hospital for a confirmed or suspected infection by SARS-CoV-2 from February 2020 to February 2021 were retrospectively evaluated.
View Article and Find Full Text PDFBackground: The use of remdesivir has demonstrated a significant reduction in the time to recovery in patients with COVID-19. However, the impact on mortality is still controversial. Therefore, it is necessary to evaluate whether there is a specific subgroup of patients in whom an active antiviral therapy also reduces the mortality.
View Article and Find Full Text PDFImportance: Identifying undetected clinical signs is imperative in the prevention of SARS-CoV-2.
Objective: To establish the prevalence of clinical gustatory and olfactory dysfunctions in patients with COVID-19 pneumonia. Clinical outcomes and recovery rates associated with gustatory and olfactory dysfunctions were also assessed.
Article Synopsis
- The study investigated how treatments like anti-IL-6 biologics and corticosteroids affect the risk of hospital-acquired infections in COVID-19 patients.
- A case-control framework was used, comparing 71 COVID-19 patients with infections to 142 matched controls without infections.
- Key findings highlighted that severe comorbidities, like chronic liver disease and invasive mechanical ventilation, dramatically increased infection risk, while inflammatory response modifiers showed no impact on hospital-acquired infections.
Background: To evaluate the efficacy and safety of long-term use of tedizolid in osteoarticular infections.
Methods: Multicentric retrospective study (January 2017-March 2019) of osteoarticular infection cases treated with tedizolid. Failure: clinical worsening despite antibiotic treatment or the need of suppressive treatment.
Ribotype 027 Clostridioides difficile infection presented as a traveller's diarrhoea.
Enferm Infecc Microbiol Clin (Engl Ed)
April 2020
Objectives: To evaluate the levels of the serum gamma globulin fraction in proteinograms as a biomarker to assess the severity, and to predict the mortality and new exacerbations in patients admitted for an exacerbation of a COPD.
Patients And Methods: The VIRAE study was carried out on a cohort of patients hospitalized for an exacerbation of probable infectious origin of COPD over a period of 2 years. The levels of the serum gamma globulin fraction were analyzed in the proteinogram of 120 patients.