Publications by authors named "Lai Khin Wee"

With the increasing availability of diverse healthcare data sources, such as medical images and electronic health records, there is a growing need to effectively integrate and fuse this multimodal data for comprehensive analysis and decision-making. However, despite its potential, multimodal data fusion in healthcare remains limited. This review paper provides an overview of existing literature on multimodal data fusion in healthcare, covering 69 relevant works published between 2018 and 2024.

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Background: Bacterial image analysis plays a vital role in various fields, providing valuable information and insights for studying bacterial structural biology, diagnosing and treating infectious diseases caused by pathogenic bacteria, discovering and developing drugs that can combat bacterial infections, . As a result, it has prompted efforts to automate bacterial image analysis tasks. By automating analysis tasks and leveraging more advanced computational techniques, such as deep learning (DL) algorithms, bacterial image analysis can contribute to rapid, more accurate, efficient, reliable, and standardised analysis, leading to enhanced understanding, diagnosis, and control of bacterial-related phenomena.

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The quantitative analysis of pulsed-chemical exchange saturation transfer (CEST) using a full model-based method is computationally challenging, as it involves dealing with varying RF values in pulsed saturation. A power equivalent continuous approximation of B power was usually applied to accelerate the analysis. In line with recent consensus recommendations from the CEST community for pulsed-CEST at 3T, particularly recommending a high RF saturation power (B = 2.

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This project employs artificial intelligence, including machine learning and deep learning, to assess COVID-19 readmission risk in Malaysia. It offers tools to mitigate healthcare resource strain and enhance patient outcomes. This study outlines a methodology for classifying COVID-19 readmissions.

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Background: Breast cancer remains a pressing global health concern, necessitating accurate diagnostics for effective interventions. Deep learning models (AlexNet, ResNet-50, VGG16, GoogLeNet) show remarkable microcalcification identification (>90%). However, distinct architectures and methodologies pose challenges.

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Epilepsy is a chronic, non-communicable disease caused by paroxysmal abnormal synchronized electrical activity of brain neurons, and is one of the most common neurological diseases worldwide. Electroencephalography (EEG) is currently a crucial tool for epilepsy diagnosis. With the development of artificial intelligence, multi-view learning-based EEG analysis has become an important method for automatic epilepsy recognition because EEG contains difficult types of features such as time-frequency features, frequency-domain features and time-domain features.

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Article Synopsis
  • An ischemic stroke activates complex signaling that can lead to neuronal death, prompting research into NOE(-1.6 ppm) as a tool for understanding ischemic injury.
  • The study used advanced MRI techniques on rats after a middle cerebral artery occlusion to measure different imaging parameters related to tissue damage.
  • Results indicated that NOE(-1.6 ppm) provides valuable insights into ischemic tissue by revealing areas affected by lipid damage, which could help differentiate four zones of tissue damage and improve diagnosis and treatment strategies.*
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Debates persist regarding the impact of Stain Normalization (SN) on recent breast cancer histopathological studies. While some studies propose no influence on classification outcomes, others argue for improvement. This study aims to assess the efficacy of SN in breast cancer histopathological classification, specifically focusing on Invasive Ductal Carcinoma (IDC) grading using Convolutional Neural Networks (CNNs).

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Background And Objective: Knee osteoarthritis (OA) is a debilitating musculoskeletal disorder that causes functional disability. Automatic knee OA diagnosis has great potential of enabling timely and early intervention, that can potentially reverse the degenerative process of knee OA. Yet, it is a tedious task, concerning the heterogeneity of the disorder.

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Background: Renal cancer is one of the leading causes of cancer-related deaths worldwide, and early detection of renal cancer can significantly improve the patients' survival rate. However, the manual analysis of renal tissue in the current clinical practices is labor-intensive, prone to inter-pathologist variations and easy to miss the important cancer markers, especially in the early stage.

Methods: In this work, we developed deep convolutional neural network (CNN) based heterogeneous ensemble models for automated analysis of renal histopathological images without detailed annotations.

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Breast cancer is commonly diagnosed with mammography. Using image segmentation algorithms to separate lesion areas in mammography can facilitate diagnosis by doctors and reduce their workload, which has important clinical significance. Because large, accurately labeled medical image datasets are difficult to obtain, traditional clustering algorithms are widely used in medical image segmentation as an unsupervised model.

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Background: The advancement of biomedical research generates myriad healthcare-relevant data, including medical records and medical device maintenance information. The COVID-19 pandemic significantly affects the global mortality rate, creating an enormous demand for medical devices. As information technology has advanced, the concept of intelligent healthcare has steadily gained prominence.

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Background: The environment has been significantly impacted by rapid urbanization, leading to a need for changes in climate change and pollution indicators. The 4IR offers a potential solution to efficiently manage these impacts. Smart city ecosystems can provide well-designed, sustainable, and safe cities that enable holistic climate change and global warming solutions through various community-centred initiatives.

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Oil palm is a key agricultural resource in Malaysia. However, palm disease, most prominently basal stem rot caused at least RM 255 million of annual economic loss. Basal stem rot is caused by a fungus known as .

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Gastric cancer is a leading cause of cancer-related deaths worldwide, underscoring the need for early detection to improve patient survival rates. The current clinical gold standard for detection is histopathological image analysis, but this process is manual, laborious, and time-consuming. As a result, there has been growing interest in developing computer-aided diagnosis to assist pathologists.

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Knee osteoarthritis is one of the most common musculoskeletal diseases and is usually diagnosed with medical imaging techniques. Conventionally, case identification using plain radiography is practiced. However, we acknowledge that knee osteoarthritis is a 3D complexity; hence, magnetic resonance imaging will be the ideal modality to reveal the hidden osteoarthritis features from a three-dimensional view.

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Alzheimer's disease (AD) is a neurodegenerative disorder that causes memory degradation and cognitive function impairment in elderly people. The irreversible and devastating cognitive decline brings large burdens on patients and society. So far, there is no effective treatment that can cure AD, but the process of early-stage AD can slow down.

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Cardiac health diseases are one of the key causes of death around the globe. The number of heart patients has considerably increased during the pandemic. Therefore, it is crucial to assess and analyze the medical and cardiac images.

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Assistive technology for the differently abled and older adults has made remarkable achievements in providing rehabilitative, adaptive, and assistive devices. It provides huge assistance for people with physical impairments to lead a better self-reliant daily life, in terms of mobility, education, rehabilitation, etc. This technology ranges from simple hand-held devices to complex robotic accessories which promote the individual's independence.

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The segmentation of the left ventricle (LV) is one of the fundamental procedures that must be performed to obtain quantitative measures of the heart, such as its volume, area, and ejection fraction. In clinical practice, the delineation of LV is still often conducted semi-automatically, leaving it open to operator subjectivity. The automatic LV segmentation from echocardiography images is a challenging task due to poorly defined boundaries and operator dependency.

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Article Synopsis
  • Caregivers and family members play a big role in helping autistic children feel good emotionally and mentally.
  • A study was done to see how different colors and lights affect the mood and actions of autistic kids, using a survey with 87 participants.
  • It turns out that calm colors and softer lighting help make autistic children feel better, while bright colors and strong lights can sometimes cause them to act differently or feel uncomfortable.
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Purpose: Mental health assessments that combine patients' facial expressions and behaviors have been proven effective, but screening large-scale student populations for mental health problems is time-consuming and labor-intensive. This study aims to provide an efficient and accurate intelligent method for further psychological diagnosis and treatment, which combines artificial intelligence technologies to assist in evaluating the mental health problems of college students.

Materials And Methods: We propose a mixed-method study of mental health assessment that combines psychological questionnaires with facial emotion analysis to comprehensively evaluate the mental health of students on a large scale.

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Forecasting the severity of occupational injuries shall be all industries' top priority. The use of machine learning is theoretically valuable to assist the predictive analysis, thus, this study attempts to propose a feature-optimized predictive model for anticipating occupational injury severity. A public database of 66,405 occupational injury records from OSHA is analyzed using five sets of machine learning models: Support Vector Machine, K-Nearest Neighbors, Naïve Bayes, Decision Tree, and Random Forest.

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Computer-aided Invasive Ductal Carcinoma (IDC) grading classification systems based on deep learning have shown that deep learning may achieve reliable accuracy in IDC grade classification using histopathology images. However, there is a dearth of comprehensive performance comparisons of Convolutional Neural Network (CNN) designs on IDC in the literature. As such, we would like to conduct a comparison analysis of the performance of seven selected CNN models: EfficientNetB0, EfficientNetV2B0, EfficientNetV2B0-21k, ResNetV1-50, ResNetV2-50, MobileNetV1, and MobileNetV2 with transfer learning.

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