Publications by authors named "Lagiou A"

People who suffer from severe mental health disorders are also at high risk of developing other serious health problems. Unhealthy lifestyle behaviors combined with low self-care and low health literacy among people with severe mental health disorders highlight the need to design health promotion interventions in this population group. A qualitative study was carried out with the aim of investigating the perceptions among mental health professionals on the health promotion needs of people with severe mental health disorders through the co-production approach.

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Background: The aim of the present study was to develop and validate a self-reported instrument exploring the perceived potential contribution and impact of a community-university partnership (CUP) on the local community's quality of life.

Methods: A 13-item questionnaire was developed and administered to a convenience sample of 65 residents of the municipality of Egaleo, a metropolitan area of Athens, Greece, where the main campus of the University of West Attica is located. The questionnaire was self-administered and filled in at two different time points by the same participants.

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In this multi-ancestry genome-wide association study (GWAS) and fine mapping study of head and neck squamous cell carcinoma (HNSCC) subsites, we analysed 19,073 cases and 38,857 controls and identified 29 independent novel loci. We provide robust evidence that a 3' UTR variant in (rs78378222, T>G) confers a 40% reduction in odds of developing overall HNSCC. We further examine the gene-environment relationship of and variants demonstrating their effects act through both smoking and alcohol use.

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Informal childcare supply may have a double-edged effect on grandparents' health and quality of life, as different aspects of it may exceed or subceed the capacity of the older persons, in various ways. This study aimed to assess the effect of grandparenting on physical activity, nutrition, and quality of life of older people. The study involved 152 grandparents ≥65 years old (69.

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Article Synopsis
  • The study aimed to explore the relationship between endothelial glycocalyx damage and arterial stiffness with retinal changes in patients with type 2 diabetes mellitus (DM) using advanced imaging techniques like OCT and OCT-A.
  • Involving 65 patients with DM and 42 control participants, a variety of clinical examinations were conducted, including measuring microvessel characteristics and assessing arterial stiffness.
  • Key findings indicate that patients with DM had increased endothelial glycocalyx damage and arterial stiffness, which were linked to significant changes in retinal structures, including increased foveal avascular zone and diabetic macular edema.
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HPV-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) are recognized as distinct entities. There remains uncertainty surrounding the causal effects of smoking and alcohol on the development of these two cancer types. Here we perform multivariable Mendelian randomization (MR) to evaluate the causal effects of smoking and alcohol on the risk of HPV-positive and HPV-negative HNSCC in 3431 cases and 3469 controls.

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Excessive smartphone use and dependence on social media give rise to multiple issues that negatively affect the overall well-being of individuals. Nomophobia is characterized as a "digital disease" due to the unlimited use of smartphone devices. The aim of this study is to examine smartphone use and social media involvement in association with nomophobia and psychological traits (i.

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Obesity is an emerging threat and a current challenge for children and adolescents worldwide. The aim of the present work was to evaluate the relationship between the Dietary Antioxidant Index (DAI) and the weight status of students in early adolescence. A sample of 1580 students aged 10-12 years from 47 primary schools in Greece were enrolled.

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Tobacco smoke, alone or combined with alcohol, is the predominant cause of head and neck cancer (HNC). Here, we further explore how tobacco exposure contributes to cancer development by mutational signature analysis of 265 whole-genome sequenced HNC from eight countries. Six tobacco-associated mutational signatures were detected, including some not previously reported.

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Introduction/objectives: Systematic identification of persons with palliative care needs constitutes a major challenge for promoting palliative care in all levels of the health system, including primary care. The aim of this study was to translate, cross-culturally adapt, and content validate Supportive and Palliative Care Indicators Tool (SPICT) for use in the Greek primary care context. Secondary objectives were to probe the use of SPICT-GR in exemplary case vignettes, to discuss the clarity and comprehensibility of its content as well as the appropriateness, acceptability, and feasibility of the tool within the Greek primary care.

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Background: Previous studies suggest that dietary vitamin C is inversely associated with gastric cancer (GC), but most of them did not consider intake of fruit and vegetables. Thus, we aimed to evaluate this association within the Stomach cancer Pooling (StoP) Project, a consortium of epidemiological studies on GC.

Methods: Fourteen case-control studies were included in the analysis (5362 cases, 11,497 controls).

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Objective: To explore and describe social and healthcare professionals' perceptions and educational needs in relation to domestic violence and its prevention.

Methods: A qualitative research was conducted in three European countries. Two multidisciplinary focus group interviews were conducted (in each country) among professionals and higher education teachers in the field of social and health care.

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Smartphones with their numerous applications have become essential daily equipment, prompting scientific research to deal with the impact of their use on psychosocial health. Under this spectrum, the aim of the present cross-sectional study was to examine the association between nomophobia and the negative emotional states of depression, anxiety, and stress, in relation to self-esteem and sociodemographic data, among the young adult population. The study sample consisted of 1408 young adults aged 18-25 years, participating on a voluntary basis with an online anonymous questionnaire.

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Article Synopsis
  • Gastric cancer is more common in men, and this study explores whether reproductive factors and menopausal hormone therapy (MHT) might protect women from it.
  • The analysis included over 2,000 individuals with gastric cancer and more than 7,000 controls across various studies, revealing that longer fertility duration and MHT use may reduce cancer risk in women.
  • The findings suggest a link between reproductive health and decreased gastric cancer risk, highlighting the need for further research on hormonal effects in different stages of a woman’s life.
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The development of overweight and obesity during late childhood and early adolescence is one of the most critical issues in public health. Additionally, over the past few years, the consumption of protein has tended to increase in both children and adults. The present study aimed to evaluate whether the protein type, either plant- or animal-sourced, as well as the quantity consumed, could potentially have a relationship with excess body weight in children.

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Introduction And Methodology: Health Promotion is moving into a new technological era, that of Digital Health Promotion (DHP). The aim was to collect systematic reviews of digital health promotion interventions.

Results And Discussion: 147 articles met the criteria and were included in the present study.

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Despite its significant decline in the general population, smoking remains endemic and highly prevalent among people with mental disorders. The impact of smoking-attributable morbidity on life expectancy is significant since, in comparison to the general population, people with severe mental disorders have a 15-20-year reduction in life expectancy. A cross-sectional study was conducted among 1015 people with mental disorders through personal interviews.

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A growing proportion of head and neck cancer (HNC), especially oropharyngeal cancer (OPC), is caused by human papillomavirus (HPV). There are several markers for HPV-driven HNC, one being HPV early antigen serology. We aimed to investigate the diagnostic accuracy of HPV serology and its performance across patient characteristics.

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Nomophobia is characterized as apprehension of being apart from smartphone, which causes the user to seek proximity with the device. The purpose of this study was to explore the prevalence and factors associated to nomophobia among young adults in Athens, the capital city of Greece. A cross-sectional study was performed on a sample of 1408 young adults aged 18-25 years.

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Domestic violence affects people of all socioeconomic backgrounds and education levels and can happen to anyone. It is a public health issue that needs to be addressed with health and social care professionals playing an essential role in prevention and early intervention. These professionals need to be prepared through proper education.

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Background: Due to growing pressure on the health care system, a shift in rehabilitation to home settings is essential. However, efficient support for home-based rehabilitation is lacking. The COVID-19 pandemic has further exacerbated these challenges and has affected individuals and health care professionals during rehabilitation.

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Background: Yoghurt can modify gastrointestinal disease risk, possibly acting on gut microbiota. Our study aimed at exploring the under-investigated association between yoghurt and gastric cancer (GC).

Methods: We pooled data from 16 studies from the Stomach Cancer Pooling (StoP) Project.

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The consumption of ultra-processed foods (UPFs) is high along with the prevalence of emotional and behavioral problems among children and adolescents. The present study sought to investigate the synergetic effect of soft drinks and sweet/salty snacks consumption, and the moderating role of obesity on preadolescents' emotions and behavior. A cross-sectional study was conducted among 1728 Greek preadolescents aged 10-12 and their parents, during the school years 2014-2016.

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An epidemiological study was conducted among 1728 10-12-year-old students (55.1% girls) and their parents during 2014-2016 in Greece. This study aimed to identify the dominant clusters of physical activity/sedentariness among preadolescents and investigate their association with self-reported sources of stress.

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The aim of the present work was two-fold. Firstly, to evaluate the association between the consumption of ultra-processed beverages (UPB) on preadolescents' likelihood of being obese. Secondly, to investigate the potential impact of family and school environmental stressors on this unhealthy lifestyle habit.

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