A machine learning approach in a monocentric cohort for predicting primary refractory disease in Diffuse Large B-cell lymphoma patients.

Introduction: Primary refractory disease affects 30-40% of patients diagnosed with DLBCL and is a significant challenge in disease management due to its poor prognosis. Predicting refractory status could greatly inform treatment strategies, enabling early intervention. Various options are now available based on patient and disease characteristics.

SARS-CoV-2 Seroprevalence among Healthcare Workers after the First and Second Pandemic Waves.

The Grand Hôpital de Charleroi is a large non-academic Belgian hospital that treated a large number of COVID-19 inpatients. In the context of this pandemic, all professions-combined healthcare workers (HCWs), and not only direct caregivers, are a frontline workforce in contact with suspected and confirmed COVID-19 cases and seem to be a high-risk group for exposure. The aim of our study was to estimate the prevalence of anti-SARS-CoV-2 antibodies in HCWs in our hospital after the first and second pandemic waves and to characterize the distribution of this seroprevalence in relation to various criteria.

Health Care Pollution And Public Health Damage In The United States: An Update.

An up-to-date assessment of environmental emissions in the US health care sector is essential to help policy makers hold the health care industry accountable to protect public health. We update national-level US health-sector emissions. We also estimate state-level emissions for the first time and examine associations with state-level energy systems and health care quality and access metrics.

Transforming The Medical Device Industry: Road Map To A Circular Economy.

A circular economy involves maintaining manufactured products in circulation, distributing resource and environmental costs over time and with repeated use. In a linear supply chain, manufactured products are used once and discarded. In high-income nations, health care systems increasingly rely on linear supply chains composed of single-use disposable medical devices.

Improving early audiological intervention via newborn hearing screening in Belgium.

Background: Newborn hearing screening programs aim to lower the ages at audiological intervention among hearing-impaired children. In Wallonia and Brussels (Belgium), audiological intervention data are not collected in the screening program, and the ages at initiating audiological care have never been assessed. This study aimed to assess the evolution in the ages at initiating audiological intervention in the context of a newborn hearing screening program implementation.

Assessment of competence: developing trends and ethical considerations.

Purpose Of Review: This review explores new concepts in competency assessment in anesthesiology, the associated ethical challenges, and directions for new research.

Recent Findings: Many new tools for the assessment of competence are currently in development to address changes in medical education curricula. The assessment of competence currently focuses on technical skills, nontechnical skills, and the interaction of both through the use of simulation, with increasing emphasis on validity and reliability testing.

Organisation of newborn hearing screening programmes in the European Union: widely implemented, differently performed.

Background: Implementation of newborn hearing screening programmes is widely recommended and programme organisational designs may differ in practice. The objective of this article was to establish an overview of the newborn hearing screening programmes in the 28 countries of the European Union on four topics (policy-decision, financing, general designs, organisational features).

Methods: National or regional programme coordinators completed an online self-administered questionnaire focusing on protocol description and programme organisation.

Newborn hearing screening programme in Belgium: a consensus recommendation on risk factors.

Background: Understanding the risk factors for hearing loss is essential for designing the Belgian newborn hearing screening programme. Accordingly, they needed to be updated in accordance with current scientific knowledge. This study aimed to update the recommendations for the clinical management and follow-up of newborns with neonatal risk factors of hearing loss for the newborn screening programme in Belgium.

The Surgical Care Improvement Project Antibiotic Guidelines: Should We Expect More Than Good Intentions?

Since 2006, the Surgical Care Improvement Project (SCIP) has promoted 3 perioperative antibiotic recommendations designed to reduce the incidence of surgical site infections. Despite good evidence for the efficacy of these recommendations, the efforts of SCIP have not measurably improved the rates of surgical site infections. We offer 3 arguments as to why SCIP has fallen short of expectations.

Main outcomes of a newborn hearing screening program in Belgium over six years.

Objective: To present the outcomes of the newborn hearing screening program in Belgium (French-speaking area) since its implementation and to analyze its evolution between 2007 and 2012 in the neonatal population without reported risk factors for hearing loss.

Methods: The study was descriptive and based on a retrospective analysis of six annual databases (2007-2012) from the newborn hearing screening program. The main outcomes were identified: prevalence of reported hearing impairment; coverage rates (first and second test, follow-up); proportions of conclusive screening tests; referral rate.

Putting newborn hearing screening on the political agenda in Belgium: local initiatives toward a community programme - a qualitative study.

Background: The Kingdon model, based on the convergence of three streams (problem, policy, and politics) and the opening of a policy window, analyses the process by which a health issue is placed on the political agenda. We used this model to document the political agenda-setting process of the newborn hearing screening programme in Belgium.

Methods: A qualitative study based on a document review and on semi-directed interviews was carried out.

The organisation of universal newborn hearing screening in the Wallonia-Brussels Federation.

Objective: A universal newborn hearing screening programme based on the voluntary participation of maternity hospitals has been implemented in the Wallonia-Brussels Federation since November 2006. This paper presents the results of this programme and its evolution since its implementation (2007-2011).

Method: Two-step screening by automated otoacoustic emissions is performed on newborns without risk factors for hearing loss and, if abnormal responses or risk factor(s) are found, auditory brainstem response audiometry is performed.

Prediction of rate and severity of adverse perioperative outcomes: "normal accidents" revisited.

The American Society of Anesthesiologists Physical Status classification system has been shown to predict the frequency of perioperative morbidity and mortality despite known subjectivity, inconsistent application, and exclusion of many perioperative confounding variables. The authors examined the relationship between the American Society of Anesthesiologists Physical Status and both the frequency and the severity of adverse events over a 10-year period in an academic anesthesiology practice. The American Society of Anesthesiologists Physical Status is predictive of not only the frequency of adverse perioperative events, but also the severity of adverse events.

Indicators of anesthesia safety and quality.

In 1999, the Institute of Medicine shocked the world by claiming that medical error was among the leading causes of death in the United States. In contrast, anesthesiology was cited as an area in which there have been impressive gains in safety and quality. The mechanisms to which these impressive gains have been attributed include practice guidelines, anesthesia simulators, and benchmarking.