Publications by authors named "Laetitia Ferrando"

Article Synopsis
  • Autism spectrum disorder (ASD) is influenced by a variety of factors, and the ELENA cohort aims to explore how these factors interact to identify risk factors and create targeted treatments for children with ASD.
  • This multicenter study, conducted between 2012 and 2019, analyzed 876 newly diagnosed children using direct assessments and parent-reported questionnaires, focusing on developmental, biological, psychosocial, and socio-demographic elements.
  • Key findings reveal baseline clinical characteristics and highlight the importance of a comprehensive biopsychosocial approach in enhancing the quality of life and interventions for children with ASD, advocating for an interdisciplinary strategy to support the ASD community.
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Introduction: The elevated rates of neurodevelopmental disorders (NDDs) among siblings of children with autism spectrum disorder (ASD) raise concerns about their developmental monitoring and development. The main aim of this study is to assess the feasibility and acceptability of a standardised screening process on a large sample of siblings.

Methods And Analysis: This prospective study will assess the feasibility of a selective and multi-stage screening process for NDD performed on 384 siblings of children with confirmed ASD.

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Autism Spectrum Disorder (ASD) is an early onset neurodevelopmental disorder in which the first signs generally emerge at approximately 12 months of age but its diagnosis is feasible only from the age of 18 months. According to the literature, the average age of diagnosis ranges from 2.7 to 7.

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Article Synopsis
  • - Multiple Drug Hypersensitivity Syndrome (MDHS) is defined as confirmed drug allergies to at least two unrelated medications, but there's limited research on its prevalence and characteristics.
  • - In a study analyzing data from an Allergy Unit between 1996 and 2018, 45 patients were confirmed to have MDHS, with a significant portion linked to immunologic mechanisms and categorized into types IV and I allergies.
  • - The findings highlight MDHS as a rare condition, making up only 2.5% of patients with suspected drug hypersensitivity, emphasizing the need for skin testing and drug provocation tests for accurate diagnosis.
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