Aerobic physical training does not condition against strenuous exercise-induced changes in immune function but modulates T cell proliferative responses.

Background: Exercise-induced stress induces considerable changes in the immune system. To better understand the mechanisms related to these immune changes during acute and chronic physical stress, we studied the effects of aerobic physical training (APT) on several parameters of the immune system.

Methods: Previously untrained males (18-25 years of age) were divided into a group that was subjected to 6 months of APT (N.