Publications by authors named "Ladislav Soukup"

Background: Hypertension is one of the most prevalent chronic non-communicable diseases and affects more than 60% of individuals over 60 years of age. Additionally, hypertension is a prominent risk factor for the development of cardiovascular diseases (CVDs). Human body composition is both the result and predictor of an individual's health status, and hypertension has consistently been shown to be more prevalent among obese individuals.

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Pulse wave velocity is a commonly used parameter for evaluating arterial stiffness and the overall condition of the cardiovascular system. The main goal of this study was to establish a methodology to test and validate multichannel bioimpedance as a suitable method for whole-body evaluations of pulse waves. We set the proximal location over the left carotid artery and eight distal locations on both the upper and lower limbs.

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The main goal of this study was to make a comparison of aortic flow timing obtained by PW Doppler in four aortic sections with timing of - dZ/dt max obtained by bioimpedance measurement in nine locations on the thorax and neck. This knowledge is essential for determination of which bioimpedance channel could be used as a proximal for evaluation of pulse wave velocity (PWV) from the beginning of the ascending aorta or another aortic section. Time intervals between the Doppler flow and bioimpedance information (- dZ/dt max) were compared.

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Purpose: The aim of this proof-of-concept study is to introduce new high-dynamic ECG technique with potential to detect temporal-spatial distribution of ventricular electrical depolarization and to assess the level of ventricular dyssynchrony.

Methods: 5-kHz 12-lead ECG data was collected. The amplitude envelopes of the QRS were computed in an ultra-high frequency band of 500-1000 Hz and were averaged (UHFQRS).

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The design, properties, and possible diagnostic contribution of a multichannel bioimpedance monitor (MBM) with three independent current sources are presented in this paper. The simultaneous measurement of bioimpedance at 18 locations (the main part of the body, legs, arms, and neck) provides completely new information, on the basis of which more precise haemodynamic parameters can be obtained. The application of the MBM during various haemodynamic stages, such as resting in a supine position, tilting, exercise stress, and various respiration manoeuvres, is demonstrated.

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