Physical activity induces depression-like behavior in intact male rats.

Testosterone affects behavior. Whether regular physical training does influence these effects is unknown. The assumption that testosterone induces muscular hypertrophy if combined with physical training has not been confirmed experimentally.

Cella media distance in human brain in relation to age and gender.

Aims: To determine whether simple linear measurements can be used as an accurate and reproducible replacement of the volumetric ones.

Methods: We measured the cella media distance (CM1) and the distance between the right and left human brain surfaces (CM2)--measured along the CM1 line--in the groups of women (F) and men (M) who were divided according to diagnoses into three subgroups (F1-3 and M1-3). Examinations were carried out under standardized conditions: axial serial CT (Computed Tomography) images, in 4 mm layers (333 patients).

Effect of prenatal phenytoin administration on the fine structure of rat myocardium and aorta.

Phenytoin (PHT) is an antiepileptic drug known to have teratogenic effects. The aim of this study was to examine the ultrastructure of the left ventricle, the left atrium, and the aorta of 3-month-old offspring and 4-month-old mother animals after oral PHT (150 mg/kg/day) administration to Wistar/DV rats on days 7-18 of gestation. Electron microscopy of the myocardium revealed a heterogeneous population of cardiomyocytes with conventional architecture, and hypoxia/ischemia-like subcellular changes.

Fluorescence of hematoxylin and eosin-stained histological sections of the human spleen.

A major problem in the morphometric evaluation of human spleen is the simple but reliable determination of the border between T-cell and B-cell dependent areas, and other structures of the spleen. It was investigated whether cryostat sections of frozen surgical specimens of the human spleen and sections of paraffin-embedded specimens could be used for this purpose after being stained with haematoxylin and eosin and mounted in autofluorescence-free medium for fluorescence microscopical evaluation. Comparison was made with sections that were immunohistochemically-stained for fibronectin and collagens type II and type IV.