Publications by authors named "Ladan Sadeghi"
Background: Zirconium nanoparticles are used as health agents, pharmaceutical carriers, and in dental and orthopedic implants.
Objective: This studyaimed to investigate the effects of Zirconium oxide nanoparticles on the process of spermatogenesis in rat.
Materials And Methods: In this experimental study, 32 male Wistar rats (150-200 gr), with range of age 2.
Objectives: Wharton jelly mesenchymal stem cells are good candidates for application in different aspects of regenerative medicine, and their long-time banking is important. In this study, the effects of trehalose, ascorbic acid, and Y-27632 on proliferation and survival rate of these cells after cryopreservation were investigated.
Materials And Methods: Mesenchymal stem cells were isolated from human umbilical cord Wharton jelly and frozen using a slow-rate cooling process.
Aim: To investigate the differentiation of human Wharton's jelly derived mesenchymal stromal cells (WJ-MSCs) to insulin producing clusters (IPC) this study was conducted.
Methods: The umbilical cords samples were collected from full term caesarian section mothers and the WJ-MSCS were cultured from tissue explants in High glucose-Dulbecco's Modified Eagle Medium (H-DMEM); H-DMEM supplemented with 10% fetal bovine serum (FBS) and antibiotics. The expression of CD90, CD44, CD105, CD34 and CD133 as well as osteogenic and adipogenic differentiation of cells in appropriate medium were also evaluated.
Background: Mesenchymal stem cells (MSCs) possess a wide range of immunomodulatory functions mostly in immune cells including dendritic cells (DCs). DCs are the key cells in the immune response and play an important role in initiating cell-mediated immunity.
Objective: To evaluate the immunomodulatory effects of MSCs supernatant on maturation and function of DCs.