Realizing quantum convolutional neural networks on a superconducting quantum processor to recognize quantum phases.

Quantum computing crucially relies on the ability to efficiently characterize the quantum states output by quantum hardware. Conventional methods which probe these states through direct measurements and classically computed correlations become computationally expensive when increasing the system size. Quantum neural networks tailored to recognize specific features of quantum states by combining unitary operations, measurements and feedforward promise to require fewer measurements and to tolerate errors.

Realizing repeated quantum error correction in a distance-three surface code.

Quantum computers hold the promise of solving computational problems that are intractable using conventional methods. For fault-tolerant operation, quantum computers must correct errors occurring owing to unavoidable decoherence and limited control accuracy. Here we demonstrate quantum error correction using the surface code, which is known for its exceptionally high tolerance to errors.

Barriers and facilitators linked to discharge destination following inpatient rehabilitation after traumatic brain injury in older adults: a qualitative study.

Purpose: To identify facilitators and barriers associated with returning home for older adults having received inpatient rehabilitation after traumatic brain injury (TBI).

Methods: A qualitative design was used. Five older patients with TBI and four family caregivers were interviewed and six healthcare professionals participated in a focus group.

Implementation of Conditional Phase Gates Based on Tunable ZZ Interactions.

High fidelity two-qubit gates exhibiting low cross talk are essential building blocks for gate-based quantum information processing. In superconducting circuits, two-qubit gates are typically based either on rf-controlled interactions or on the in situ tunability of qubit frequencies. Here, we present an alternative approach using a tunable cross-Kerr-type ZZ interaction between two qubits, which we realize with a flux-tunable coupler element.

[Which place for point-of-care screening tests in the diagnosis of hepatitis C infection among drug users?].

Hepatitis C is a severe disease, which often evolves into chronicity and for which there is no vaccine available. Therefore its screening is essential, especially among drug users who are the main reservoir of the hepatitis C virus (HCV). Current guidelines for screening are based on the detection of total anti-HCV antibodies (Ab) by means of third generation EIA.

Molecular Basis for the Regulation of Transcriptional Coactivator p300 in Myogenic Differentiation.

Skeletal myogenesis is a highly ordered process which specifically depends on the function of transcriptional coactivator p300. Previous studies have established that Akt/protein kinase B (PKB), a positive regulator of p300 in proliferating cells, is also important for proper skeletal muscle development. Nevertheless, it is not clear as to how the p300 is regulated by myogenic signaling events given that both p300 and Akt are involved in many cellular processes.

Anaerobic digestion and gasification coupling for wastewater sludge treatment and recovery.

Sewage sludge management is an energy intensive process. Anaerobic digestion contributes to energy efficiency improvement but is limited by the biological process. A review has been conducted prior to experimentation in order to evaluate the mass and energy balances on anaerobic digestion followed by gasification of digested sludge.

Activation of GATA4 gene expression at the early stage of cardiac specification.

Currently, there are no effective treatments to directly repair damaged heart tissue after cardiac injury since existing therapies focus on rescuing or preserving reversibly damaged tissue. Cell-based therapies using cardiomyocytes generated from stem cells present a promising therapeutic approach to directly replace damaged myocardium with new healthy tissue. However, the molecular mechanisms underlying the commitment of stem cells into cardiomyocytes are not fully understood and will be critical to guide this new technology into the clinic.

Induction of Pax3 gene expression impedes cardiac differentiation.

Cell-based therapies using pluripotent stem cells hold great promise as regenerative approaches to treat many types of diseases. Nevertheless many challenges remain and, perhaps foremost, is the issue of how to direct and enhance the specification and differentiation of a desired cell type for potential therapeutics. We have examined the molecular basis for the inverse correlation of cardiac and skeletal myogenesis in small molecule-enhanced stem cell differentiation.

Histone deacetylase inhibitor valproic acid as a small molecule inducer to direct the differentiation of pluripotent stem cells.

Pluripotent stem cells can be directed into myogenic differentiation by small molecular inducers, which preferentially activate muscle-specific transcription networks. Here we describe how to efficiently direct the differentiation of pluripotent P19 cells into skeletal muscle lineage by using histone deacetylase inhibitor, valproic acid and the ligand of retinoic acid receptor, all-trans retinoic acid.

Contribution of retinoid X receptor signaling to the specification of skeletal muscle lineage.

Pluripotent stem cells possess a tremendous potential for the treatment of many diseases because of their capacity to differentiate into a variety of cell lineages. However, they provide little promise for muscle-related diseases, mainly because of the lack of small molecule inducers to efficiently direct myogenic conversion. Retinoic acid, acting through the retinoic acid receptor (RAR) and retinoid X receptor (RXR), affects stem cell fate determination in a concentration-dependent manner, but it only has a modest efficacy on the commitment of ES cells into skeletal muscle lineage.

Characterization of aromatic properties of old-style cheese starters.

Old-style cheese starters were evaluated to determine their ability to produce cheese aroma compounds. Detailed analyses of the aroma-producing potential of 13 old-style starter cultures were undertaken. The proteolytic profile of the starters was established by an accelerated ripening study using a model cheese slurry and compared with those of a commercial aromatic starter and commercial Cheddar cheeses.

[Total parenteral nutrition for recurrent episodes of acute pancreatitis during pregnancy. A case report and literature review].

We report on a 35-year-old woman who underwent at 15 weeks of pregnancy exclusive parenteral nutrition for recurrent episodes of acute pancreatitis. She had a pancreatico-jejunal anastomosis stenosis secondary to cephalic duodenopancreatectomy. Nocturnal exclusive parenteral nutrition was used 79 days during pregnancy and 12 days during post-partum.

[Natural cycle in vitro fertilization cycle in poor responders].

Since the beginning of IVF, natural cycle In Vitro Fertilization (NC-IVF) has been largely replaced by IVF with ovarian stimulation. However, natural cycle IVF has several advantages: low cost, no risk of ovarian hyper stimulation syndrome, very low risk of multiple pregnancy. Nevertheless, natural cycle IVF is less effective with a high risk of cancellation due to premature rise of LH, and an increased risk of failed oocyte retrieval.

Incorporation of salicylic acid derivatives to hydrophilic copolymer systems with biomedical applications.

Hydrogels based on polymeric derivatives of salicylic acid have been prepared for biomedical applications by free radical copolymerization of 2-hydroxy-4-methacrylamidobenzoic acid, 4HMA, and 2-hydroxy-5-methacrylamidobenzoic acid, 5HMA, with 2- hydroxyethylmethacrylate, HEMA, in a wide range of compositions. The reactivity ratios of 4HMA and 5HMA with HEMA in radical copolymerization processes have been determined from their 1H NMR spectra by applying linearization methods and non-linear least square treatments. Tgs of the corresponding copolymers were analyzed by DSC.

Prevalence of bovine virus diarrhoea virus infection in Belgian white blue cattle in southern Belgium.

A study was conducted in Southern Belgium to determine the prevalence of bovine viral diarrhoea virus (BVDV) infection in Belgian White Blue herds. Blood samples were taken from 9685 cattle, representing all the stock on 61 farms, by local veterinarians to screen for persistently infected animals and to determine their serological status against BVDV. Some of the herds (42.

Steroid regulation of oncofetal fibronectin expression in human cytotrophoblasts.

Oncofetal fibronectin (onfFN) is a uniquely glycosylated form of FN suggested to play a critical role in uterine/placental adherence during pregnancy. In the present study we have examined steroid regulation of onfFN in highly purified preparations (> or = 95%) of cytotrophoblasts isolated from human term placentas. Based on immunoassays, relative to controls, treatment of cytotrophoblasts with 10(-6) M medroxyprogesterone acetate (MPA) down-regulated media levels of onfFN 25, 53, 59, and 62% on days 1, 2, 3 and 4, respectively.

A further study of the holoblastic cleavage field.

The division of holoblastically cleaving eggs was modelled by Goodwin & Trainor in terms of a minimization principle applied to the generalized surface free energy of a spherical surface, expressed in terms of an order parameter. Their calculations led to a cumulative description of the sequence of horizontal and vertical cleavage lines or planes in terms of the nodal lines of spherical harmonics. In this paper we give a complete treatment, first of the numerical regularities exhibited by holoblastic cleavage resulting in a group-theoretic formulation, and secondly of the calculations which arise from Goodwin & Trainor's model.