Dual-mode interaction between quercetin and DNA-damaging drugs in cancer cells.

Background: DNA-damaging drugs constitute standard chemotherapy regimen for advanced colorectal cancer. Here, the interactions between quercetin and 5-fluorouracil (5-FU), etoposide, and camptothecin were examined in cancer cells.

Materials And Methods: HCT116 colorectal or PPC1 prostate cancer cells were treated with quercetin and the drugs.