A pilot study of the pharmacokinetics of continuous magnesium infusion in critically ill patients.

The pharmacokinetics and haemodynamic effect of continuous magnesium infusion in non-cardiac intensive care unit (ICU) patients are poorly understood. We aimed to measure serum and urine magnesium levels during bolus and continuous infusion in critically ill adults, compare serum levels with those of a control population, and assess its haemodynamic effect. Pharmacokinetic study A single tertiary adult ICU.