Publications by authors named "Lacey Marshall-Lund"

Article Synopsis
  • Porcine circovirus type 3 (PCV3) has been linked to abortions and systemic diseases in pigs but the full scope of its effects isn't well understood.
  • This study analyzed 25 cases of pigs with PCV3, examining tissues for lesions and detecting PCV3 mRNA through in situ hybridization (ISH).
  • The heart showed the most damage, with significant lesions also detected in the lungs, kidneys, liver, spleen, and lymph nodes; recommendations for testing include focusing on heart, lung, and lymphoid tissues to help diagnose PCV3-related diseases.
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Background: There is limited information on the distribution of virulence-associated genes (VAGs) in U.S. Streptococcus suis isolates, resulting in little understanding of the pathogenic potential of these isolates.

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The objective of this study was to determine if serum amyloid A (SAA), a major acute-phase protein, could help support the diagnosis of equine proliferative enteropathy (EPE) caused by Lawsonia intracellularis infection in foals. Archived serum samples from 101 foals with enteric signs and hypoproteinemia were available for SAA testing. Based on immunodiagnostics for L.

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Next generation sequencing (NGS) can be applied to identify and characterize the entire set of microbes within a sample. However, this platform does not provide a morphological context or specific association between the viral or bacterial sequences detected and the histological lesions. This limitation has generated uncertainty whether the sequences identified by NGS are actually contributing or not for the clinical outcome.

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