A putative Ariadne-like ubiquitin ligase is required for Dictyostelium discoideum development.

The Dictyostelium rbrA gene encodes a putative Ariadne ubiquitin ligase. rbrA(-) cells form defective slugs that cannot phototax. Prestalk cell numbers are reduced in rbrA(-) slugs, and these prestalk cells do not localize to the tip of slugs.